Ageing Phenotype Observation—Data Type 2 : OB_003108
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Saccharomyces cerevisiae | ||||||||||||||
Strain | : | YPK9 | ||||||||||||||
Gene | : |
|
||||||||||||||
Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | decreased | ||||||||||||||
Change | : | -18.40% | ||||||||||||||
Observed Lifespan | : | 17.3 | ||||||||||||||
Reference Lifespan | : | 21.2 | ||||||||||||||
Lifespan Unit | : | divisions | ||||||||||||||
Measure | : | mean | ||||||||||||||
Temperature | : | 30 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | mata | ||||||||||||||
Description | : | Deletion of RAS2 decreases replicative lifespan by 18.4% in the absense of mitochondrial DNA (rho0). Deletion of RAS2 thus blocks the lifespan extension normally observed in rho0 strains. | ||||||||||||||
Observation Stable ID | : | OB_003108 | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 4488) | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kirchman PA, Miceli MV, West RL, Jiang JC, Kim S, Jazwinski SM:
Prohibitins and Ras2 protein cooperate in the maintenance of mitochondrial function during yeast aging.
Acta Biochim Pol. 2003; 50: 1039-56.
PubMed (ID: 14739993), doi:0350041039
MeSH Terms: Fungal Proteins; Mitochondria/metabolism; Repressor Proteins/metabolism; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae/metabolism; ras Proteins/metabolism