Ageing Phenotype Observation—Data Type 2 : OB_003167
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||
Strain | : | N2 | ||||||||||||||
Gene | : |
|
||||||||||||||
Compound | : | |||||||||||||||
Other Ageing Factor | : |
|
||||||||||||||
Significant Lifespan Effect | : | none | ||||||||||||||
Change | : | 0.00% | ||||||||||||||
Observed Lifespan | : | 35 | ||||||||||||||
Reference Lifespan | : | 35 | ||||||||||||||
Lifespan Unit | : | days | ||||||||||||||
Measure | : | median | ||||||||||||||
Temperature | : | 20 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | DR-FD and mutation of eat-2 increase lifespan and thermotolerance by similar mechanisms. DR-FD increases the lifespan of eat-2(ad465) mutants, but not beyond that of wild-type. Median lifespans: N2 Fed, 25 days; N2 DR-FD, 35 days; eat-2 Fed, 29 days; eat-2 DR-FD, 35 days. There is no significant difference in DR in lifespan of eat-2 mutants and N2. | ||||||||||||||
Observation Stable ID | : | OB_003167 | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 4563) | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein TL, Smith ED, Tsuchiya M, Welton KL, Thomas JH, Fields S, Kennedy BK, Kaeberlein M:
Lifespan extension in Caenorhabditis elegans by complete removal of food.
Aging Cell. 2006; 5: 487-94.
PubMed (ID: 17081160), doi:10.1111/j.1474-9726.2006.00238.x
MeSH Terms: Aging/physiology; Caenorhabditis elegans/metabolism; Food Deprivation/physiology; Longevity/physiology