Ageing Phenotype Observation—Data Type 2 : OB_003218
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||
Strain | : | N2 | ||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | decreased | ||||||||||||||
Change | : | -7.02% | ||||||||||||||
Observed Lifespan | : | 31.8 | ||||||||||||||
Reference Lifespan | : | 34.2 | ||||||||||||||
Lifespan Unit | : | days | ||||||||||||||
Measure | : | mean | ||||||||||||||
Temperature | : | 16 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | CHIL significantly increased average lifespan in sod mutants relative to standard temperature lifespan of mutant. There was no significant difference between mutant and N2 controls at 16 degrees. | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 4628) | ||||||||||||||
Observation Stable ID | : | OB_003218 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Yen K, Patel HB, Lublin AL, Mobbs CV:
SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold.
Mech Ageing Dev. 2009; 130: 173-8.
PubMed (ID: 19059428), doi:10.1016/j.mad.2008.11.003
MeSH Terms: Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/enzymology; Caloric Restriction; Cold Temperature; Gene Silencing; Mutation; Stress, Physiological/genetics; Superoxide Dismutase/metabolism