Ageing Phenotype Observation—Data Type 2 : OB_003273
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Drosophila melanogaster | |||||||||||||||||||||
Strain | : | S1-32 | |||||||||||||||||||||
Gene | : |
|
|||||||||||||||||||||
Compound | : | ||||||||||||||||||||||
Other Ageing Factor | : | ||||||||||||||||||||||
Significant Lifespan Effect | : | increased | |||||||||||||||||||||
Change | : | 15.91% | |||||||||||||||||||||
Observed Lifespan | : | 51 | |||||||||||||||||||||
Reference Lifespan | : | 44 | |||||||||||||||||||||
Lifespan Unit | : | days | |||||||||||||||||||||
Measure | : | mean | |||||||||||||||||||||
Temperature | : | 25 | |||||||||||||||||||||
Temperature Unit | : | ℃ | |||||||||||||||||||||
Sex/Mating Type | : | female | |||||||||||||||||||||
Description | : | Double expression of Dmp53-259H/dFoxo leads to a 16% increase in mean lifespan over uninduced control flies. | |||||||||||||||||||||
Source | : | Lifespan Observations Database (ID: 4697) | |||||||||||||||||||||
Observation Stable ID | : | OB_003273 | |||||||||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Bauer JH, Chang C, Bae G, Morris SN, Helfand SL:
Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster.
Mech Ageing Dev. 2010; 131: 193-201.
PubMed (ID: 20117129), PubMed Central (ID: PMC2988653), doi:10.1016/j.mad.2010.01.007
MeSH Terms: Drosophila/metabolism; Longevity/physiology; Transcription Factors/metabolism; Tumor Suppressor Protein p53/metabolism