Ageing Phenotype Observation—Data Type 2 : OB_003607
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||
Strain | : | CRH-1 NULL | ||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | none | ||||||||||||||
Change | : | 0.00% | ||||||||||||||
Observed Lifespan | : | 18 | ||||||||||||||
Reference Lifespan | : | 18 | ||||||||||||||
Lifespan Unit | : | days | ||||||||||||||
Measure | : | median | ||||||||||||||
Temperature | : | 20 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | RNAi of crtc-1 has no significant effect on lifespan of crh-1 (nn3315) nulls. | ||||||||||||||
Observation Stable ID | : | OB_003607 | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 5041) | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A:
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
Nature. 2011; 470: 404-8.
PubMed (ID: 21331044), PubMed Central (ID: PMC3098900), doi:10.1038/nature09706
MeSH Terms: AMP-Activated Protein Kinases/metabolism; Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/physiology; Calcineurin/metabolism; Cyclic AMP Response Element-Binding Protein/metabolism; Longevity/physiology; Trans-Activators/metabolism; Transcription Factors/metabolism