Ageing Phenotype Observation—Data Type 2 : OB_004202
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Anopheles stephensi | ||||||||||||||
Strain | : | |||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | decreased | ||||||||||||||
Change | : | -29.63% | ||||||||||||||
Observed Lifespan | : | 19 | ||||||||||||||
Reference Lifespan | : | 27 | ||||||||||||||
Lifespan Unit | : | days | ||||||||||||||
Measure | : | mean | ||||||||||||||
Temperature | : | |||||||||||||||
Temperature Unit | : | |||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | A. stephensi expressing an active variant of the mosquito Akt under the control of the midgut-specific carboxypeptidase (CP) promoter had a reduced life span relative to control animals. | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 890) | ||||||||||||||
Observation Stable ID | : | OB_004202 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Corby-Harris V, Drexler A, Watkins de Jong L, Antonova Y, Pakpour N, Ziegler R, Ramberg F, Lewis EE, Brown JM, Luckhart S, Riehle MA:
Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoes.
PLoS Pathog. 2010; 6: e1001003.
PubMed (ID: 20664791), PubMed Central (ID: PMC2904800), doi:10.1371/journal.ppat.1001003
MeSH Terms: Anopheles/parasitology; Host-Parasite Interactions; Life Cycle Stages; Malaria/parasitology; Proto-Oncogene Proteins c-akt/metabolism