Ageing Phenotype Observation—Data Type 2 : OB_004355
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||
Strain | : | N2 | ||||||
Gene | : | |||||||
Compound | : |
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Other Ageing Factor | : |
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Significant Lifespan Effect | : | increased | ||||||
Change | : | 7.74% | ||||||
Observed Lifespan | : | 16.7 | ||||||
Reference Lifespan | : | 15.5 | ||||||
Lifespan Unit | : | days | ||||||
Measure | : | mean | ||||||
Temperature | : | 20 | ||||||
Temperature Unit | : | ℃ | ||||||
Sex/Mating Type | : | hermaphrodite | ||||||
Description | : | When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. | ||||||
Source | : | Lifespan Observations Database (ID: 2330) | ||||||
Observation Stable ID | : | OB_004355 | ||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Yamawaki TM, Berman JR, Suchanek-Kavipurapu M, McCormick M, Gaglia MM, Lee SJ, Kenyon C:
The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling.
PLoS Biol. 2010; 8:
PubMed (ID: 20824162), PubMed Central (ID: PMC2930862), doi:10.1371/journal.pbio.1000468
MeSH Terms: Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/physiology; Cholestenes/pharmacology; Germ Cells/cytology; Longevity/physiology; Receptors, Cytoplasmic and Nuclear/metabolism; Signal Transduction