Ageing Phenotype Observation—Data Type 2 : OB_004436
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||
Strain | : | N2 | ||||||
Gene | : | |||||||
Compound | : |
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Other Ageing Factor | : | |||||||
Significant Lifespan Effect | : | increased | ||||||
Change | : | 16.04% | ||||||
Observed Lifespan | : | 21.7 | ||||||
Reference Lifespan | : | 18.7 | ||||||
Lifespan Unit | : | days | ||||||
Measure | : | mean | ||||||
Temperature | : | 20 | ||||||
Temperature Unit | : | ℃ | ||||||
Sex/Mating Type | : | hermaphrodite | ||||||
Description | : | osm-3 mutants displayed an extended lifespan and were resistant to the lifespan extension caused by ethosuximide. | ||||||
Source | : | Lifespan Observations Database (ID: 3911) | ||||||
Observation Stable ID | : | OB_004436 | ||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Collins JJ, Evason K, Pickett CL, Schneider DL, Kornfeld K:
The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan.
PLoS Genet. 2008; 4: e1000230.
PubMed (ID: 18949032), PubMed Central (ID: PMC2565500), doi:10.1371/journal.pgen.1000230
MeSH Terms: Anticonvulsants/pharmacology; Caenorhabditis elegans/drug effects; Caenorhabditis elegans/physiology; Ethosuximide/pharmacology; Sensory Receptor Cells/drug effects; Sensory Receptor Cells/physiology