Ageing Phenotype Observation—Data Type 2 : OB_004523
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||
Strain | : | |||||||
Gene | : | |||||||
Compound | : |
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Other Ageing Factor | : | |||||||
Significant Lifespan Effect | : | increased | ||||||
Change | : | 38.46% | ||||||
Observed Lifespan | : | 18 | ||||||
Reference Lifespan | : | 13 | ||||||
Lifespan Unit | : | days | ||||||
Measure | : | mean | ||||||
Temperature | : | 25 | ||||||
Temperature Unit | : | ℃ | ||||||
Sex/Mating Type | : | |||||||
Description | : | The addition of carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP) lengthened lifespan approximately 38%. | ||||||
Observation Stable ID | : | OB_004523 | ||||||
Source | : | Lifespan Observations Database (ID: 4860) | ||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Ibrahim Y, Oikonomou D, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP:
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.
Aging Cell. 2008; 7: 260-9.
PubMed (ID: 18221415), doi:10.1111/j.1474-9726.2008.00371.x
MeSH Terms: Caenorhabditis elegans/enzymology; Lactoylglutathione Lyase/biosynthesis; Lactoylglutathione Lyase/deficiency; Longevity; Mitochondria/enzymology; Protein Modification, Translational