Ageing Phenotype Observation—Data Type 2 : OB_004543
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Mus musculus | ||||||
Strain | : | SHR | ||||||
Gene | : | |||||||
Compound | : |
|
||||||
Other Ageing Factor | : | |||||||
Significant Lifespan Effect | : | none | ||||||
Change | : | 0.00% | ||||||
Observed Lifespan | : | 636 | ||||||
Reference Lifespan | : | 636 | ||||||
Lifespan Unit | : | days | ||||||
Measure | : | median | ||||||
Temperature | : | 22 | ||||||
Temperature Unit | : | ℃ | ||||||
Sex/Mating Type | : | |||||||
Description | : | Metformin treatment started at the age of 15 months had no significant effect on median lifespan relative to control. | ||||||
Source | : | Lifespan Observations Database (ID: 4981) | ||||||
Observation Stable ID | : | OB_004543 | ||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Anisimov VN, Berstein LM, Popovich IG, Zabezhinski MA, Egormin PA, Piskunova TS, Semenchenko AV, Tyndyk ML, Yurova MN, Kovalenko IG, Poroshina TE:
If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice.
Aging (Albany NY). 2011; 3: 148-57.
PubMed (ID: 21386129), PubMed Central (ID: PMC3082009)
MeSH Terms: Hypoglycemic Agents/pharmacology; Life Expectancy; Longevity/drug effects; Metformin/pharmacology; Neoplasms/prevention & control