Ageing Phenotype Observation—Data Type 1 : OB_005397
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | RNA interference increased mean lifespan by 11%. In hus-1 mutants, RNA interference of cep-1 did not increase lifespan, suggesting both genes influence lifespan through the same pathway. | ||||
PubMed | : | 17895432 | ||||
Observation Stable ID | : | OB_005397 | ||||
Source | : | GenAge | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Arum O, Johnson TE:
Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity.
J Gerontol A Biol Sci Med Sci. 2007; 62: 951-9.
PubMed (ID: 17895432)
MeSH Terms: Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans/genetics; Genes, Helminth; Longevity/genetics; Tumor Suppressor Protein p53/genetics