Ageing Phenotype Observation—Data Type 2 : OB_005406
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||
Strain | : | |||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | increased | ||||||||||||||
Change | : | 20.00% | ||||||||||||||
Observed Lifespan | : | |||||||||||||||
Reference Lifespan | : | |||||||||||||||
Lifespan Unit | : | |||||||||||||||
Measure | : | maximum | ||||||||||||||
Temperature | : | |||||||||||||||
Temperature Unit | : | |||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | Loss-of-function mutation increased maximum lifespan by about 20%. It did not extend the lifespan of daf-16(RNAi) animals. TOR RNA interference further extended lifespan. | ||||||||||||||
Source | : | GenAge | ||||||||||||||
Observation Stable ID | : | OB_005406 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C:
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans.
Aging Cell. 2007; 6: 95-110.
PubMed (ID: 17266679), doi:10.1111/j.1474-9726.2006.00267.x
MeSH Terms: Caenorhabditis elegans/genetics; Caenorhabditis elegans/metabolism; Gene Expression Regulation/genetics; Longevity/genetics; Protein Biosynthesis/genetics; Saccharomyces cerevisiae Proteins/metabolism