Ageing Phenotype Observation—Data Type 1 : OB_005419
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | Knockouts have an extended lifespan phenotype (40-50%) and are defective in dauer formation due to defects in daf-2 receptor signalling pathway in ciliatedsensory neurons. There was no additive effect of the ifta-2 mutation on the daf-2 longevity phenotype. | ||||
PubMed | : | 16968739 | ||||
Source | : | GenAge | ||||
Observation Stable ID | : | OB_005419 | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Schafer JC, Winkelbauer ME, Williams CL, Haycraft CJ, Desmond RA, Yoder BK:
IFTA-2 is a conserved cilia protein involved in pathways regulating longevity and dauer formation in Caenorhabditis elegans.
J Cell Sci. 2006; 119: 4088-100.
PubMed (ID: 16968739), doi:10.1242/jcs.03187
MeSH Terms: Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans Proteins/physiology; Caenorhabditis elegans/genetics; Cilia/genetics; Longevity/genetics; rab GTP-Binding Proteins/genetics; rab GTP-Binding Proteins/physiology