Ageing Phenotype Observation—Data Type 1 : OB_005446
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Mus musculus | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | Irs2 brain-specific knockout mice were overweight, hyperinsulinemic, glucose intolerant, yet more active and lived up to 18% longer. | ||||
PubMed | : | 17641201 | ||||
Source | : | GenAge | ||||
Observation Stable ID | : | OB_005446 | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Taguchi A, Wartschow LM, White MF:
Brain IRS2 signaling coordinates life span and nutrient homeostasis.
Science. 2007; 317: 369-72.
PubMed (ID: 17641201), doi:10.1126/science.1142179
MeSH Terms: Brain/metabolism; Glucose/metabolism; Homeostasis; Intracellular Signaling Peptides and Proteins/metabolism; Longevity; Phosphoproteins/metabolism; Signal Transduction