Ageing Phenotype Observation—Data Type 1 : OB_005475
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Mus musculus | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | Disruption results in infertility and signs of premature ageing such as a short lifespan, arteriosclerosis, skin atrophy, osteoporosis, and emphysema. | ||||
PubMed | : | 9363890 | ||||
Observation Stable ID | : | OB_005475 | ||||
Source | : | GenAge | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, Iwasaki H, Iida A, Shiraki-Iida T, Nishikawa S, Nagai R, Nabeshima YI:
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
Nature. 1997; 390: 45-51.
PubMed (ID: 9363890), doi:10.1038/36285
MeSH Terms: Aging/genetics; Membrane Proteins/genetics