Ageing Phenotype Observation—Data Type 1 : OB_005488
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Mus musculus | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | Inactivation extended fertile potential and minimized age-related health problems, including bone and muscle loss, excess fat deposition, alopecia, cataracts, deafness, increased anxiety, and selective attention deficit. It did not extend lifespan. | ||||
PubMed | : | 17360389 | ||||
Observation Stable ID | : | OB_005488 | ||||
Source | : | GenAge | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Perez GI, Jurisicova A, Wise L, Lipina T, Kanisek M, Bechard A, Takai Y, Hunt P, Roder J, Grynpas M, Tilly JL:
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice.
Proc Natl Acad Sci USA. 2007; 104: 5229-34.
PubMed (ID: 17360389), PubMed Central (ID: PMC1817832), doi:10.1073/pnas.0608557104
MeSH Terms: Aging/physiology; Fertility/physiology; bcl-2-Associated X Protein/deficiency