Ageing Phenotype Observation—Data Type 1 : OB_005525
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | lys-8 appears to inhibit the growth of gld-1 tumours. RNA interference reduced mean lifespan up to 29% in wild type animals, up to 19% in daf-2 mutants, and up to 15% in daf-2/gld-1 mutants. It also reduced maximum lifespan 12% in daf-2 mutants and 25% in daf-2/gld-1 mutants. | ||||
PubMed | : | 17934462 | ||||
Observation Stable ID | : | OB_005525 | ||||
Source | : | GenAge | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Pinkston-Gosse J, Kenyon C:
DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans.
Nat Genet. 2007; 39: 1403-9.
PubMed (ID: 17934462), doi:10.1038/ng.2007.1
MeSH Terms: Aging/genetics; Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans/genetics; Gene Expression Regulation, Developmental; Neoplasms/pathology; Transcription Factors/genetics