Ageing Phenotype Observation—Data Type 1 : OB_005676
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Drosophila melanogaster | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | Expression of dominant-negative versions of p53 in adult neurons extended lifespan by 58% in females and 32% in males and increased resistance to genotoxic stress. | ||||
PubMed | : | 16303568 | ||||
Source | : | GenAge | ||||
Observation Stable ID | : | OB_005676 | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Bauer JH, Poon PC, Glatt-Deeley H, Abrams JM, Helfand SL:
Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span.
Curr Biol. 2005; 15: 2063-8.
PubMed (ID: 16303568), doi:10.1016/j.cub.2005.10.051
MeSH Terms: Drosophila Proteins/metabolism; Drosophila melanogaster/physiology; Longevity/physiology; Neurons/metabolism; Tumor Suppressor Protein p53/metabolism