Ageing Phenotype Observation—Data Type 1 : OB_005714
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||
Gene | : |
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Other Ageing Factor | : | |||||
Description | : | PHA-4 may play a role in the life-extending effects of dietary restriction. RNA interference decreased lifespan of wild-type worms, but not of daf-2 mutants or of animals with defective electron transport chains. Overexpression slightly increased longevity. | ||||
PubMed | : | 17476212 | ||||
Observation Stable ID | : | OB_005714 | ||||
Source | : | GenAge | ||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A:
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans.
Nature. 2007; 447: 550-5.
PubMed (ID: 17476212), doi:10.1038/nature05837
MeSH Terms: Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/physiology; Caloric Restriction; Diet; Longevity/physiology; Trans-Activators/metabolism