Ageing Phenotype Observation—Data Type 2 : OB_006300
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Mus musculus | ||||||||||||||
Strain | : | |||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | decreased | ||||||||||||||
Change | : | |||||||||||||||
Observed Lifespan | : | |||||||||||||||
Reference Lifespan | : | |||||||||||||||
Lifespan Unit | : | |||||||||||||||
Measure | : | unknown | ||||||||||||||
Temperature | : | |||||||||||||||
Temperature Unit | : | |||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | Dysregulations in the alternative splicing of the fibronectin EDA exon resulted in a reduction of mean and maximal lifespan. | ||||||||||||||
Source | : | GenAge | ||||||||||||||
Observation Stable ID | : | OB_006300 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Muro AF, Chauhan AK, Gajovic S, Iaconcig A, Porro F, Stanta G, Baralle FE:
Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan.
J Cell Biol. 2003; 162: 149-60.
PubMed (ID: 12847088), PubMed Central (ID: PMC2172721), doi:10.1083/jcb.200212079
MeSH Terms: Aging/metabolism; Alternative Splicing/genetics; Exons/genetics; Fibronectins/biosynthesis; Fibronectins/genetics; Skin/injuries; Skin/metabolism; Wound Healing/genetics