Ageing Phenotype Observation—Data Type 2 : OB_007587
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Drosophila melanogaster | ||||||||||||||
Strain | : | |||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | decreased | ||||||||||||||
Change | : | -13.00% | ||||||||||||||
Observed Lifespan | : | |||||||||||||||
Reference Lifespan | : | |||||||||||||||
Lifespan Unit | : | |||||||||||||||
Measure | : | maximum | ||||||||||||||
Temperature | : | |||||||||||||||
Temperature Unit | : | |||||||||||||||
Sex/Mating Type | : | |||||||||||||||
Description | : | RNA interference shortened maximum lifespan by 13% and resulted in increased sensitivity to oxidative stress and motor impairments. | ||||||||||||||
Source | : | GenAge | ||||||||||||||
Observation Stable ID | : | OB_007587 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Lavara-Culebras E, Paricio N:
Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits.
Gene. 2007; 400: 158-65.
PubMed (ID: 17651920), doi:10.1016/j.gene.2007.06.013
MeSH Terms: Drosophila Proteins/genetics; Life Expectancy; Motor Activity/genetics; Oxidative Stress