Ageing Phenotype Observation—Data Type 1 : OB_007972
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species |
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Saccharomyces cerevisiae |
Gene |
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Gene Symbol |
NCBI Gene ID |
GIS1 |
851670 |
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Other Ageing Factor |
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Other Ageing Factor Name |
Dietary restriction |
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Description |
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Deletion of GIS1 increases replicative lifespan by 25% in the alpha strain [ 19030232] and causes major although not complete reversion of chronological lifespan extension by 0.5% glucose restriction [ 18225956]. |
PubMed |
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18225956 |
Source |
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GenDR |
Observation Stable ID |
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OB_007972 |
Download |
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XML |
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, Longo VD:
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9.
PLoS Genet. 2008; 4: e13.
PubMed (ID: 18225956), PubMed Central (ID: PMC2213705), doi:10.1371/journal.pgen.0040013
MeSH Terms: Caloric Restriction; Cyclic AMP-Dependent Protein Kinases/metabolism; Saccharomyces cerevisiae Proteins/metabolism; Saccharomyces cerevisiae/enzymology; Transcription Factors/metabolism; ras Proteins/metabolism
Sources
Ageing-related Data Sources
Additional Data Sources