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Genes List - Experimental And Computational Evidence

NOTE:

Ageing phenotype observations are considered as experimental analysis. They confirm or reject the ageing relevance for particular ageing factor(s). For genes that are homologous to known ageing-relevant genes there is thus far no experimental evidence. They are considered as candidate genes.
Due to the different data structures of ageing phenotype observation data integrated from other databases we subdivide these observations into type 1 and 2. Observations of type 1 contain the phenotype data mostly unseparated within a single description. Observations of type 2 contain lifespan data in a more structured form (e.g.: separated into lifespan effect, lifespan change, lifespan value). Currently there might be an overlap between the observations of type 1 and 2 from the same source, namely GenAge. But we are working on a reduction of this overlap.

Ageing Relevance:

yes (Exp. Analysis)
yes, but no ageing factor assigned (Exp. Analysis)
no (Exp. Analysis)
putative (Comp. Analysis)

1 ... 100

Legend:

#EGHG:
Number of Experimentally Confirmed Ageing-related Genes In Homology Group

#

Gene Symbol

NCBI Gene ID

Species

Gene Synonyms

Ageing Relevance Analysis

Homology Group Genes

#EGHG

Homology Source

Ageing Factor Stable ID

Eef1e1 | elongation factor p18 | eukaryotic translation elongation factor 1 epsilon 1 | eukaryotic translation elongation factor 1 epsilon-1 | multisynthase complex auxiliary component p18 | multisynthetase complex auxiliary component p18
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
EEF1E1	Bos taurus	617105
EEF1E1	Canis lupus familiaris	478717
EEF1E1	Gallus gallus	420865
EEF1E1	Homo sapiens	9521
EEF1E1	Macaca mulatta	695426
Eef1e1	Mus musculus	66143
EEF1E1	Pan troglodytes	462423
Eef1e1	Rattus norvegicus	291057
wu:fe14c11	Danio rerio	565440

[HomoloGene icon]

HomoloGene homology group 3161

AF_000174

EEF-2 | EEF2 | EF-2 | EF2 | ELONGATION FACTOR 2 | elongation factor 2 | EUKARYOTIC TRANSLATION ELONGATION FACTOR 2 | eukaryotic translation elongation factor 2 | POLYPEPTIDYL-tRNA TRANSLOCASE | polypeptidyl-tRNA translocase
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AGOS_AFR142C	Eremothecium gossypii	4621940
AT3G12915.1	Arabidopsis thaliana	3768815
EEF2	Bos taurus	281138
EEF2	Canis lupus familiaris	476744
EEF2	Gallus gallus	396325
EEF2	Homo sapiens	1938
EEF2	Macaca mulatta	721806
Eef2	Mus musculus	13629
Eef2	Rattus norvegicus	29565
eef2l2	Danio rerio	336168
EFT1	Saccharomyces cerevisiae	854301
EFT2	Saccharomyces cerevisiae	851993
eft201	Schizosaccharomyces pombe	3361483
eft202	Schizosaccharomyces pombe	2539544
KLLA0E02993g	Kluyveromyces lactis	2893753
LOC100614367	Pan troglodytes	100614367
MGG_01742	Magnaporthe oryzae	2679180
NCU07700	Neurospora crassa	3878434
Os02g0519900	Oryza sativa	4329493
Os04g0118400	Oryza sativa	4334959

[HomoloGene icon]

HomoloGene homology group 100816

AF_000074

Efemp1 | EGF-containing fibulin-like extracellular matrix protein 1 | epidermal growth factor-containing fibulin-like extracellular matrix protein 1 | Fbln3 | FIBL-3 | fibulin-3 | RP23-298H6.2
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
EFEMP1	Bos taurus	511566
EFEMP1	Canis lupus familiaris	474604
EFEMP1	Gallus gallus	428543
EFEMP1	Homo sapiens	2202
Efemp1	Mus musculus	216616
EFEMP1	Pan troglodytes	741921
Efemp1	Rattus norvegicus	305604
LOC100332567	Danio rerio	100332567
LOC455416	Pan troglodytes	455416

[HomoloGene icon]

HomoloGene homology group 3028

AF_000083

epidermal growth factor receptor kinase substrate 8 | EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 8 | epidermal growth factor receptor pathway substrate 8 | EPS8
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
EPS8	Bos taurus	538419
EPS8	Canis lupus familiaris	477686
EPS8	Gallus gallus	418174
EPS8	Homo sapiens	2059
EPS8	Macaca mulatta	702777
Eps8	Mus musculus	13860
EPS8	Pan troglodytes	473379
Eps8	Rattus norvegicus	312812
zgc:56041	Danio rerio	393212

[HomoloGene icon]

HomoloGene homology group 3272

AF_000121

epidermal growth factor receptor kinase substrate 8 | epidermal growth factor receptor pathway substrate 8 | Eps8
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
EPS8	Bos taurus	538419
EPS8	Canis lupus familiaris	477686
EPS8	Gallus gallus	418174
EPS8	Homo sapiens	2059
EPS8	Macaca mulatta	702777
Eps8	Mus musculus	13860
EPS8	Pan troglodytes	473379
Eps8	Rattus norvegicus	312812
zgc:56041	Danio rerio	393212

[HomoloGene icon]

HomoloGene homology group 3272

AF_000207

Saccharomyces cerevisiae

delta(14)-sterol reductase | ERG24 | Erg24p | N0593 | YNL280C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP003745	Anopheles gambiae	1271476
AGOS_AFR346W	Eremothecium gossypii	4622160
ERG24	Saccharomyces cerevisiae	855441
erg24	Schizosaccharomyces pombe	2540113
KLLA0C12265g	Kluyveromyces lactis	2892474
LBR	Bos taurus	509348
LBR	Canis lupus familiaris	490391
lbr	Danio rerio	368360
LBR	Drosophila melanogaster	37482
LBR	Gallus gallus	396285
LBR	Homo sapiens	3930
LBR	Macaca mulatta	700801
Lbr	Mus musculus	98386
LBR	Pan troglodytes	457776
Lbr	Rattus norvegicus	89789
MGG_13986	Magnaporthe oryzae	2678847
NCU08762	Neurospora crassa	3872249

[HomoloGene icon]

HomoloGene homology group 2455

AF_000132

FGF-23 | Fgf23 | fibroblast growth factor 23
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
FGF23	Bos taurus	530239
FGF23	Canis lupus familiaris	611773
fgf23	Danio rerio	494456
FGF23	Gallus gallus	428104
FGF23	Homo sapiens	8074
FGF23	Macaca mulatta	710643
Fgf23	Mus musculus	64654
FGF23	Pan troglodytes	747164
Fgf23	Rattus norvegicus	170583

[HomoloGene icon]

HomoloGene homology group 10771

AF_000266

FLT | FLT-1 | FLT1 | fms-like tyrosine kinase 1 | FMS-RELATED TYROSINE KINASE 1 | fms-related tyrosine kinase 1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | FRT | ONCOGENE FLT | tyrosine-protein kinase FRT | tyrosine-protein kinase receptor FLT | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | vascular endothelial growth factor receptor 1 | VASCULAR ENDOTHELIAL GROWTH FACTOR/VASCULAR PERMEABILITY FACTOR RECEPTOR | vascular permeability factor receptor | VEGFR-1 | VEGFR1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP008813	Anopheles gambiae	1275672
CELE_R09D1.12	Caenorhabditis elegans	174501
CELE_R09D1.13	Caenorhabditis elegans	187740
CELE_W04G5.10	Caenorhabditis elegans	173049
FLT1	Bos taurus	503620
FLT1	Canis lupus familiaris	403727
flt1	Danio rerio	544667
FLT1	Gallus gallus	374100
FLT1	Homo sapiens	2321
FLT1	Macaca mulatta	574133
Flt1	Mus musculus	14254
FLT1	Pan troglodytes	452512
Flt1	Rattus norvegicus	54251
kin-15	Caenorhabditis elegans	174498
kin-16	Caenorhabditis elegans	174499
kin-23	Caenorhabditis elegans	173050
kin-30	Caenorhabditis elegans	180032
old-1	Caenorhabditis elegans	191737
old-2	Caenorhabditis elegans	191738
Pvr	Drosophila melanogaster	34127
T01G5.1	Caenorhabditis elegans	180021
ver-1	Caenorhabditis elegans	175182
ver-3	Caenorhabditis elegans	181289
ver-4	Caenorhabditis elegans	186632
Y50D4B.6	Caenorhabditis elegans	3565593

[HomoloGene icon]

HomoloGene homology group 20463

AF_000300

FKHL16 | FORKHEAD BOX M1 | forkhead box M1 | FORKHEAD BOX M1B TRANSCRIPTION FACTOR | forkhead box protein M1 | FORKHEAD, DROSOPHILA, HOMOLOG-LIKE 16 | Forkhead, drosophila, homolog-like 16 | forkhead-related protein FKHL16 | FOXM1 | FOXM1B | hepatocyte nuclear factor 3 forkhead homolog 11 | HFH-11 | HFH11 | HNF-3 | HNF-3/fork-head homolog 11 | INS-1 | M-phase phosphoprotein 2 | MPHOSPH2 | MPM-2 reactive phosphoprotein 2 | MPP-2 | MPP2 | PIG29 | TGT3 | transcription factor Trident | TRIDENT | trident | WIN | winged-helix factor from INS-1 cells
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
FOXM1	Bos taurus	513643
FOXM1	Canis lupus familiaris	486743
foxm1	Danio rerio	394072
FOXM1	Gallus gallus	430534
FOXM1	Homo sapiens	2305
FOXM1	Macaca mulatta	708805
Foxm1	Mus musculus	14235
FOXM1	Pan troglodytes	451750
Foxm1	Rattus norvegicus	58921

[HomoloGene icon]

HomoloGene homology group 7318

AF_000277

Saccharomyces cerevisiae

FUM1 | Fum1p | fumarase FUM1 | YPL262W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP001884	Anopheles gambiae	1281238
AGOS_ACR013C	Eremothecium gossypii	4619541
FH	Bos taurus	520260
FH	Canis lupus familiaris	480092
fh	Danio rerio	393938
FH	Gallus gallus	420969
FH	Homo sapiens	2271
FH	Macaca mulatta	707542
FH	Pan troglodytes	457851
Fh	Rattus norvegicus	24368
Fh1	Mus musculus	14194
fum-1	Caenorhabditis elegans	176059
FUM1	Arabidopsis thaliana	819364
FUM1	Saccharomyces cerevisiae	855866
fum1	Schizosaccharomyces pombe	2539345
FUM2	Arabidopsis thaliana	835168
KLLA0D00902g	Kluyveromyces lactis	2893546
l(1)G0255	Drosophila melanogaster	31605
MGG_02785	Magnaporthe oryzae	2682673
NCU10008	Neurospora crassa	3875601

[HomoloGene icon]

HomoloGene homology group 115

AF_000314

GH receptor | GHBP | GHR | growth hormone binding protein | GROWTH HORMONE RECEPTOR | growth hormone receptor | serum binding protein | somatotropin receptor
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
GHR	Bos taurus	280805
GHR	Canis lupus familiaris	403721
GHR	Gallus gallus	408184
GHR	Homo sapiens	2690
GHR	Macaca mulatta	697986
Ghr	Mus musculus	14600
GHR	Pan troglodytes	471560
Ghr	Rattus norvegicus	25235
ghra	Danio rerio	100001424

[HomoloGene icon]

HomoloGene homology group 134

AF_000399

GH receptor | GHBP | Ghr | GHR/BP | growth hormone receptor | Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein) | growth hormone receptor/binding protein | somatotropin receptor
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
GHR	Bos taurus	280805
GHR	Canis lupus familiaris	403721
GHR	Gallus gallus	408184
GHR	Homo sapiens	2690
GHR	Macaca mulatta	697986
Ghr	Mus musculus	14600
GHR	Pan troglodytes	471560
Ghr	Rattus norvegicus	25235
ghra	Danio rerio	100001424

[HomoloGene icon]

HomoloGene homology group 134

AF_000398

GHRFR | GHRH receptor | GHRHR | GRF receptor | GRFR | growth hormone releasing hormone receptor | GROWTH HORMONE-RELEASING FACTOR RECEPTOR | GROWTH HORMONE-RELEASING HORMONE RECEPTOR | growth hormone-releasing hormone receptor | IGHD1B
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
GHRHR	Bos taurus	281782
GHRHR	Canis lupus familiaris	482385
GHRHR	Gallus gallus	420385
GHRHR	Homo sapiens	2692
Ghrhr	Mus musculus	14602
GHRHR	Pan troglodytes	463331
Ghrhr	Rattus norvegicus	25321
ghrhrl	Danio rerio	793334

[HomoloGene icon]

HomoloGene homology group 640

AF_000404

Ghrfr | GHRH receptor | Ghrhr | GRF receptor | GRFR | Grfr | growth hormone releasing hormone receptor | growth hormone-releasing factor receptor | growth hormone-releasing hormone receptor | lit | little
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
GHRHR	Bos taurus	281782
GHRHR	Canis lupus familiaris	482385
GHRHR	Gallus gallus	420385
GHRHR	Homo sapiens	2692
Ghrhr	Mus musculus	14602
GHRHR	Pan troglodytes	463331
Ghrhr	Rattus norvegicus	25321
ghrhrl	Danio rerio	793334

[HomoloGene icon]

HomoloGene homology group 640

AF_000408

GLUTATHIONE PEROXIDASE 4 | glutathione peroxidase 4 | glutathione peroxidase 4 (phospholipid hydroperoxidase) | GPx-4 | GPX4 | GSHPx-4 | MCSP | PHGPX | PHGPx | phospholipid hydroperoxidase | PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE | phospholipid hydroperoxide glutathione peroxidase, mitochondrial | snGPx | snPHGPx | sperm nucleus glutathione peroxidase
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AGOS_AFL039C	Eremothecium gossypii	4621742
F26E4.12	Caenorhabditis elegans	184981
gpx1	Schizosaccharomyces pombe	2540222
GPX4	Bos taurus	286809
GPX4	Gallus gallus	374056
GPX4	Homo sapiens	2879
GPX4	Macaca mulatta	705333
Gpx4	Mus musculus	625249
GPX4	Pan troglodytes	741876
Gpx4	Rattus norvegicus	29328
gpx4a	Danio rerio	352928
gpx4b	Danio rerio	352929
GPX6	Arabidopsis thaliana	826765
GPXH1	Anopheles gambiae	1274092
HYR1	Saccharomyces cerevisiae	854855
KLLA0F06732g	Kluyveromyces lactis	2894772
MGG_07460	Magnaporthe oryzae	2683380
NCU09534	Neurospora crassa	3874066
Os02g0664000	Oryza sativa	4330235
Os04g0556300	Oryza sativa	4336627
PHGPx	Drosophila melanogaster	38413
R05H10.5	Caenorhabditis elegans	187630

[HomoloGene icon]

HomoloGene homology group 90937

AF_000424

glutathione peroxidase 4 | GPx-4 | Gpx4 | GSHPx-4 | mtPHGPx | PHGPx | phospholipid hydroperoxide glutathione peroxidase | phospholipid hydroperoxide glutathione peroxidase, mitochondrial | phospholipid hydroperoxide glutathione peroxidase, nuclear | snGPx | sperm nuclei glutathione peroxidase
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AGOS_AFL039C	Eremothecium gossypii	4621742
F26E4.12	Caenorhabditis elegans	184981
gpx1	Schizosaccharomyces pombe	2540222
GPX4	Bos taurus	286809
GPX4	Gallus gallus	374056
GPX4	Homo sapiens	2879
GPX4	Macaca mulatta	705333
Gpx4	Mus musculus	625249
GPX4	Pan troglodytes	741876
Gpx4	Rattus norvegicus	29328
gpx4a	Danio rerio	352928
gpx4b	Danio rerio	352929
GPX6	Arabidopsis thaliana	826765
GPXH1	Anopheles gambiae	1274092
HYR1	Saccharomyces cerevisiae	854855
KLLA0F06732g	Kluyveromyces lactis	2894772
MGG_07460	Magnaporthe oryzae	2683380
NCU09534	Neurospora crassa	3874066
Os02g0664000	Oryza sativa	4330235
Os04g0556300	Oryza sativa	4336627
PHGPx	Drosophila melanogaster	38413
R05H10.5	Caenorhabditis elegans	187630

[HomoloGene icon]

HomoloGene homology group 90937

AF_000454

Saccharomyces cerevisiae

glutamate--cysteine ligase | GSH1 | Gsh1p | J0832 | YJL101C
Source:

Ageing Phenotype Observation—Data Type 1	GenDR
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP001512	Anopheles gambiae	1281664
GCLC	Bos taurus	512468
GCLC	Canis lupus familiaris	609822
gclc	Danio rerio	326857
Gclc	Drosophila melanogaster	53581
GCLC	Gallus gallus	421894
GCLC	Homo sapiens	2729
GCLC	Macaca mulatta	710508
Gclc	Mus musculus	14629
GCLC	Pan troglodytes	742732
Gclc	Rattus norvegicus	25283
gcs-1	Caenorhabditis elegans	174438
gcs1	Schizosaccharomyces pombe	2541881
GSH1	Saccharomyces cerevisiae	853344
KLLA0F14058g	Kluyveromyces lactis	2894885
MGG_07317	Magnaporthe oryzae	2683213
NCU01157	Neurospora crassa	3877703

[HomoloGene icon]

HomoloGene homology group 1148

AF_000468

GON-10 | HD1 | HDAC1 | HISTONE DEACETYLASE 1 | histone deacetylase 1 | REDUCED POTASSIUM DEPENDENCY 3, YEAST, HOMOLOG-LIKE 1 | reduced potassium dependency, yeast homolog-like 1 | RP4-811H24.2 | RPD3 | RPD3-LIKE 1 | RPD3L1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP006511	Anopheles gambiae	1277106
AGOS_AGR395W	Eremothecium gossypii	4623365
clr6	Schizosaccharomyces pombe	2540368
hda-1	Caenorhabditis elegans	179959
HDA9	Arabidopsis thaliana	823594
HDAC1	Bos taurus	404126
HDAC1	Canis lupus familiaris	487309
hdac1	Danio rerio	192302
HDAC1	Gallus gallus	373961
HDAC1	Homo sapiens	3065
Hdac1	Mus musculus	433759
HDAC1	Pan troglodytes	464259
HDAC1	Pan troglodytes	748850
Hdac1	Rattus norvegicus	297893
KLLA0E01981g	Kluyveromyces lactis	2894684
LOC708441	Macaca mulatta	708441
MGG_05857	Magnaporthe oryzae	2684118
NCU00824	Neurospora crassa	3880510
Rpd3	Drosophila melanogaster	38565
RPD3	Saccharomyces cerevisiae	855386

[HomoloGene icon]

HomoloGene homology group 68426

AF_000442

HELICASE, LYMPHOID-SPECIFIC | helicase, lymphoid-specific | HELLS | LSH | lymphoid-specific helicase | Nbla10143 | PASG | PROLIFERATION-ASSOCIATED SNF2-LIKE GENE | proliferation-associated SNF2-like protein | SMARCA6 | SWI/SNF-RELATED, MATRIX-ASSOCIATED, ACTIN-DEPENDENT REGULATOR OF CHROMATIN, SUBFAMILY A, MEMBER 6 | SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6 | SWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 6
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
DDM1	Arabidopsis thaliana	836808
HELLS	Bos taurus	540933
HELLS	Canis lupus familiaris	486809
hells	Danio rerio	553328
HELLS	Gallus gallus	423750
HELLS	Homo sapiens	3070
HELLS	Macaca mulatta	701598
Hells	Mus musculus	15201
HELLS	Pan troglodytes	450624
Hells	Rattus norvegicus	294071
NCU06306	Neurospora crassa	3878743

[HomoloGene icon]

HomoloGene homology group 50037

AF_000589

helicase, lymphoid specific | Hells | LSH | Lsh | lymphocyte-specific helicase | Lysh | PASG | Pasg | proliferation-associated SNF2-like | proliferation-associated SNF2-like protein | YFK8
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
DDM1	Arabidopsis thaliana	836808
HELLS	Bos taurus	540933
HELLS	Canis lupus familiaris	486809
hells	Danio rerio	553328
HELLS	Gallus gallus	423750
HELLS	Homo sapiens	3070
HELLS	Macaca mulatta	701598
Hells	Mus musculus	15201
HELLS	Pan troglodytes	450624
Hells	Rattus norvegicus	294071
NCU06306	Neurospora crassa	3878743

[HomoloGene icon]

HomoloGene homology group 50037

AF_000695

Saccharomyces cerevisiae

HCP1 | HMT1 | Hmt1p | ODP1 | RMT1 | YBR0320 | YBR034C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP003462	Anopheles gambiae	1272833
AGOS_AAR190W	Eremothecium gossypii	4618771
Art1	Drosophila melanogaster	41295
HMT1	Saccharomyces cerevisiae	852322
KLLA0B07117g	Kluyveromyces lactis	2897067
LOC719419	Macaca mulatta	719419
MGG_04584	Magnaporthe oryzae	2678111
NCU07459	Neurospora crassa	3880059
Os09g0359800	Oryza sativa	4346843
prmt-1	Caenorhabditis elegans	180326
PRMT1	Bos taurus	520388
PRMT1	Canis lupus familiaris	476411
prmt1	Danio rerio	321974
PRMT1	Homo sapiens	3276
Prmt1	Mus musculus	15469
Prmt1	Rattus norvegicus	60421
PRMT11	Arabidopsis thaliana	829072
PRMT1A	Arabidopsis thaliana	816486
rmt1	Schizosaccharomyces pombe	2543492

[HomoloGene icon]

HomoloGene homology group 21477

AF_000570

Saccharomyces cerevisiae

HOG1 | Hog1p | L2931 | L9354.2 | SSK3 | YLR113W
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP012148	Anopheles gambiae	1280530
AGOS_AGR048C	Eremothecium gossypii	4623013
HOG1	Saccharomyces cerevisiae	850803
KLLA0F20053g	Kluyveromyces lactis	2895492
LOC718976	Macaca mulatta	718976
MAPK14	Bos taurus	534492
MAPK14	Canis lupus familiaris	403856
MAPK14	Gallus gallus	421183
MAPK14	Homo sapiens	1432
Mapk14	Mus musculus	26416
MAPK14	Pan troglodytes	450161
Mapk14	Rattus norvegicus	81649
mapk14a	Danio rerio	65237
MGG_01822	Magnaporthe oryzae	2679641
Mpk2	Drosophila melanogaster	42866
MPK3	Arabidopsis thaliana	823706
NCU07024	Neurospora crassa	3878327
Os03g0285800	Oryza sativa	4332475
p38b	Drosophila melanogaster	34780
pmk-1	Caenorhabditis elegans	191743
sty1	Schizosaccharomyces pombe	2541652

[HomoloGene icon]

HomoloGene homology group 31777

AF_000631

Saccharomyces cerevisiae

HSC82 | Hsc82p | HSP90 | Hsp90 family chaperone HSC82 | YM8010.16 | YMR186W
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_AFL148C	Eremothecium gossypii	4621628
HSC82	Saccharomyces cerevisiae	855224
HSP82	Saccharomyces cerevisiae	855836
HSP90-1	Arabidopsis thaliana	835341
HSP90AA1	Bos taurus	281832
HSP90AA1	Canis lupus familiaris	480438
HSP90AA1	Gallus gallus	423463
HSP90AA1	Homo sapiens	3320
HSP90AA1	Macaca mulatta	708431
Hsp90aa1	Mus musculus	15519
HSP90AA1	Pan troglodytes	743883
Hsp90aa1	Rattus norvegicus	299331
hsp90aa1.2	Danio rerio	565155
KLLA0D12958g	Kluyveromyces lactis	2893084
MGG_06759	Magnaporthe oryzae	2684932
NCU04142	Neurospora crassa	3877462
swo1	Schizosaccharomyces pombe	2543539

[HomoloGene icon]

HomoloGene homology group 68464

AF_000651

EL52 | epididymis luminal secretory protein 52 | FLJ31884 | heat shock 86 kDa | heat shock 90kD protein 1, alpha | heat shock 90kD protein 1, alpha-like 4 | heat shock 90kD protein, alpha-like 4 | heat shock 90kDa protein 1, alpha | heat shock protein 90kDa alpha (cytosolic), class A member 1 | heat shock protein HSP 90-alpha | HEAT-SHOCK 90-KD PROTEIN 1, ALPHA | HEAT-SHOCK 90-KD PROTEIN 1, ALPHA-LIKE 4 | HEAT-SHOCK PROTEIN, 90-KD, ALPHA, CLASS A, MEMBER 1 | HSP 86 | HSP86 | Hsp89 | HSP89-ALPHA | HSP89A | Hsp90 | HSP90A | HSP90AA1 | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | LAP2 | LIPOPOLYSACCHARIDE-ASSOCIATED PROTEIN 2 | LPS-ASSOCIATED PROTEIN 2 | renal carcinoma antigen NY-REN-38
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AGOS_AFL148C	Eremothecium gossypii	4621628
HSC82	Saccharomyces cerevisiae	855224
HSP82	Saccharomyces cerevisiae	855836
HSP90-1	Arabidopsis thaliana	835341
HSP90AA1	Bos taurus	281832
HSP90AA1	Canis lupus familiaris	480438
HSP90AA1	Gallus gallus	423463
HSP90AA1	Homo sapiens	3320
HSP90AA1	Macaca mulatta	708431
Hsp90aa1	Mus musculus	15519
HSP90AA1	Pan troglodytes	743883
Hsp90aa1	Rattus norvegicus	299331
hsp90aa1.2	Danio rerio	565155
KLLA0D12958g	Kluyveromyces lactis	2893084
MGG_06759	Magnaporthe oryzae	2684932
NCU04142	Neurospora crassa	3877462
swo1	Schizosaccharomyces pombe	2543539

[HomoloGene icon]

HomoloGene homology group 68464

AF_000098

constitutive heat shock protein 70 | heat shock 70kd protein 10 | heat shock 70kD protein 8 | heat shock 70kDa protein 8 | heat shock cognate 71 kDa protein | heat shock cognate protein 54 | HEAT-SHOCK 70-KD PROTEIN 10 | HEAT-SHOCK 70-KD PROTEIN 8 | HEAT-SHOCK COGNATE PROTEIN, 71-KD | HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | HSPA8 | LAP1 | LIPOPOLYSACCHARIDE-ASSOCIATED PROTEIN 1 | lipopolysaccharide-associated protein 1 | LPS-ASSOCIATED PROTEIN 1 | LPS-associated protein 1 | N-myristoyltransferase inhibitor protein 71 | NIP71
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
Hsc70-1	Drosophila melanogaster	39542
hsp-1	Caenorhabditis elegans	178507
HSP70-5	Arabidopsis thaliana	838174
HSPA8	Bos taurus	281831
HSPA8	Canis lupus familiaris	479406
hspa8	Danio rerio	573376
HSPA8	Gallus gallus	395853
HSPA8	Homo sapiens	3312
HSPA8	Macaca mulatta	707989
Hspa8	Mus musculus	15481
HSPA8	Pan troglodytes	451629
Hspa8	Rattus norvegicus	24468
SSA4	Saccharomyces cerevisiae	856840

[HomoloGene icon]

HomoloGene homology group 68524

AF_000586

Saccharomyces cerevisiae

HST1 | Hst1p | YOL068C
Source:

Ageing Phenotype Observation—Data Type 1	GenDR
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_AEL013C	Eremothecium gossypii	4621047
HST1	Saccharomyces cerevisiae	854086
KLLA0F14663g	Kluyveromyces lactis	2895003
SIR2	Saccharomyces cerevisiae	851520

[HomoloGene icon]

HomoloGene homology group 48604

AF_000669

Saccharomyces cerevisiae

HST2 | Hst2p | LPA2C | YPL015C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP002943	Anopheles gambiae	1273019
AGOS_AGL018C	Eremothecium gossypii	4622947
HST2	Saccharomyces cerevisiae	856092
hst2	Schizosaccharomyces pombe	2538868
KLLA0F11033g	Kluyveromyces lactis	2895121
LOC100425019	Macaca mulatta	100425019
MGG_14172	Magnaporthe oryzae	5048967
NCU00523	Neurospora crassa	3879874
SIRT2	Bos taurus	504463
SIRT2	Canis lupus familiaris	612558
sirt2	Danio rerio	322309
Sirt2	Drosophila melanogaster	42414
SIRT2	Gallus gallus	548628
SIRT2	Homo sapiens	22933
Sirt2	Mus musculus	64383
SIRT2	Pan troglodytes	456013
Sirt2	Rattus norvegicus	361532

[HomoloGene icon]

HomoloGene homology group 40823

AF_000671

HD | HD GENE | HTT | HUNTINGTIN | huntingtin | huntingtin (Huntington disease) | huntington disease protein | IT15
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
HTT	Bos taurus	615059
HTT	Canis lupus familiaris	479074
htt	Danio rerio	30214
HTT	Gallus gallus	422878
HTT	Homo sapiens	3064
HTT	Macaca mulatta	700306
Htt	Mus musculus	15194
HTT	Pan troglodytes	461084
Htt	Rattus norvegicus	29424

[HomoloGene icon]

HomoloGene homology group 1593

AF_000585

HD | Hd | HD protein homolog | Hdh | Htt | htt | huntingtin | Huntington disease gene homolog | huntington disease protein homolog | IT15
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
HTT	Bos taurus	615059
HTT	Canis lupus familiaris	479074
htt	Danio rerio	30214
HTT	Gallus gallus	422878
HTT	Homo sapiens	3064
HTT	Macaca mulatta	700306
Htt	Mus musculus	15194
HTT	Pan troglodytes	461084
Htt	Rattus norvegicus	29424

[HomoloGene icon]

HomoloGene homology group 1593

AF_000584

Saccharomyces cerevisiae

IDH2 | Idh2p | isocitrate dehydrogenase (NAD(+)) IDH2 | O3326 | YOR136W | YOR3326W
Source:

Ageing Phenotype Observation—Data Type 1	GenDR
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP002728	Anopheles gambiae	1273240
AGOS_AFR137C	Eremothecium gossypii	4621935
F43G9.1	Caenorhabditis elegans	172655
IDH2	Saccharomyces cerevisiae	854303
idh2	Schizosaccharomyces pombe	2541260
IDH3A	Bos taurus	282446
IDH3A	Canis lupus familiaris	479066
idh3a	Danio rerio	393926
IDH3A	Gallus gallus	415362
IDH3A	Homo sapiens	3419
IDH3A	Macaca mulatta	677715
Idh3a	Mus musculus	67834
IDH3A	Pan troglodytes	453565
Idh3a	Rattus norvegicus	114096
IDH5	Arabidopsis thaliana	831884
IDH6	Arabidopsis thaliana	820139
KLLA0E03125g	Kluyveromyces lactis	2894289
l(1)G0156	Drosophila melanogaster	32940
MGG_01712	Magnaporthe oryzae	2679352
NCU07697	Neurospora crassa	3878431
Os01g0276100	Oryza sativa	4324442

[HomoloGene icon]

HomoloGene homology group 4037

AF_000742

Saccharomyces cerevisiae

IDP2 | Idp2p | isocitrate dehydrogenase (NADP(+)) IDP2 | L9470.12 | YLR174W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP006660	Anopheles gambiae	1277248
AGOS_AAL022W	Eremothecium gossypii	4618465
AT1G65930.1	Arabidopsis thaliana	842905
Idh	Drosophila melanogaster	44291
idh-1	Caenorhabditis elegans	177775
IDH1	Bos taurus	281235
IDH1	Canis lupus familiaris	478889
idh1	Danio rerio	100006589
IDH1	Gallus gallus	424112
IDH1	Homo sapiens	3417
IDH1	Macaca mulatta	710019
Idh1	Mus musculus	15926
IDH1	Pan troglodytes	460113
Idh1	Rattus norvegicus	24479
IDP2	Saccharomyces cerevisiae	850871
KLLA0F12342g	Kluyveromyces lactis	2894935
Os01g0654500	Oryza sativa	4324176
Os05g0573200	Oryza sativa	4339674

[HomoloGene icon]

HomoloGene homology group 21195

AF_000746

IBP1 | IGF I | IGF-I | IGF-IA | IGF-IB | IGF1 | IGF1A | IGFI | insulin-like growth factor 1 | insulin-like growth factor 1 (somatomedin C) | INSULIN-LIKE GROWTH FACTOR I | insulin-like growth factor I | insulin-like growth factor IA | insulin-like growth factor IB | mechano growth factor | MGF | SOMATOMEDIN C | somatomedin-C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
IGF1	Bos taurus	281239
IGF1	Canis lupus familiaris	610255
igf1	Danio rerio	114433
IGF1	Gallus gallus	418090
IGF1	Homo sapiens	3479
IGF1	Macaca mulatta	698444
Igf1	Mus musculus	16000
IGF1	Pan troglodytes	741055
Igf1	Rattus norvegicus	24482

[HomoloGene icon]

HomoloGene homology group 515

AF_000737

Igf-1 | Igf-I | Igf1 | insulin-like growth factor 1 | insulin-like growth factor I | somatomedin
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
IGF1	Bos taurus	281239
IGF1	Canis lupus familiaris	610255
igf1	Danio rerio	114433
IGF1	Gallus gallus	418090
IGF1	Homo sapiens	3479
IGF1	Macaca mulatta	698444
Igf1	Mus musculus	16000
IGF1	Pan troglodytes	741055
Igf1	Rattus norvegicus	24482

[HomoloGene icon]

HomoloGene homology group 515

AF_000804

Saccharomyces cerevisiae

IMP1 | INM1 | Inm1p | inositol monophosphate 1-phosphatase INM1 | YHR046C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP006570	Anopheles gambiae	1277154
CG9391	Drosophila melanogaster	40346
IMPA1	Bos taurus	281865
IMPA1	Canis lupus familiaris	477925
impa1	Danio rerio	437018
IMPA1	Gallus gallus	420199
IMPA1	Homo sapiens	3612
IMPA1	Macaca mulatta	701959
Impa1	Mus musculus	55980
Impa1	Rattus norvegicus	83523
INM1	Saccharomyces cerevisiae	856442
INM2	Saccharomyces cerevisiae	851881
LOC100613673	Pan troglodytes	100613673
MGG_06165	Magnaporthe oryzae	2684325
NCU06348	Neurospora crassa	3878521
Os03g0587000	Oryza sativa	4333347
ttx-7	Caenorhabditis elegans	172477
VTC4	Arabidopsis thaliana	821206

[HomoloGene icon]

HomoloGene homology group 4043

AF_000770

IDDM2 | ILPR | INS | INSULIN | insulin | IRDN | MODY10 | preproinsulin | PROINSULIN | proinsulin
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
INS	Bos taurus	280829
INS	Canis lupus familiaris	483665
ins	Danio rerio	30262
INS	Gallus gallus	396145
INS	Homo sapiens	3630
INS	Pan troglodytes	449570
Ins2	Mus musculus	16334
Ins2	Rattus norvegicus	24506

[HomoloGene icon]

HomoloGene homology group 173

AF_000739

Ins-2 | Ins2 | InsII | insulin II | insulin-2 | Mody | Mody4 | proinsulin
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
INS	Bos taurus	280829
INS	Canis lupus familiaris	483665
ins	Danio rerio	30262
INS	Gallus gallus	396145
INS	Homo sapiens	3630
INS	Pan troglodytes	449570
Ins2	Mus musculus	16334
Ins2	Rattus norvegicus	24506

[HomoloGene icon]

HomoloGene homology group 173

AF_000822

HIRS-1 | INSULIN RECEPTOR SUBSTRATE 1 | insulin receptor substrate 1 | IRS-1 | IRS1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
IRS1	Bos taurus	538598
IRS1	Canis lupus familiaris	486148
irs1	Danio rerio	559281
IRS1	Gallus gallus	429262
IRS1	Homo sapiens	3667
Irs1	Mus musculus	16367
IRS1	Pan troglodytes	459985
Irs1	Rattus norvegicus	25467
IRS4	Macaca mulatta	707870

[HomoloGene icon]

HomoloGene homology group 4049

AF_000613

G972R | insulin receptor substrate 1 | IRS-1 | Irs-1 | Irs1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
IRS1	Bos taurus	538598
IRS1	Canis lupus familiaris	486148
irs1	Danio rerio	559281
IRS1	Gallus gallus	429262
IRS1	Homo sapiens	3667
Irs1	Mus musculus	16367
IRS1	Pan troglodytes	459985
Irs1	Rattus norvegicus	25467
IRS4	Macaca mulatta	707870

[HomoloGene icon]

HomoloGene homology group 4049

AF_000368

INSULIN RECEPTOR SUBSTRATE 2 | insulin receptor substrate 2 | IRS-2 | IRS2
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
IRS2	Canis lupus familiaris	485548
IRS2	Gallus gallus	428017
IRS2	Homo sapiens	8660
IRS2	Macaca mulatta	698536
Irs2	Mus musculus	384783
IRS2	Pan troglodytes	452657
Irs2	Rattus norvegicus	29376

[HomoloGene icon]

HomoloGene homology group 2778

AF_000777

4PS | insulin receptor substrate 2 | Irs-2 | Irs2
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
IRS2	Canis lupus familiaris	485548
IRS2	Gallus gallus	428017
IRS2	Homo sapiens	8660
IRS2	Macaca mulatta	698536
Irs2	Mus musculus	384783
IRS2	Pan troglodytes	452657
Irs2	Rattus norvegicus	29376

[HomoloGene icon]

HomoloGene homology group 2778

AF_000025

Jun proto-oncogene related gene d | Jun proto-oncogene related gene d1 | Jun-d | Jund | JunD-FL isoform | Jund1 | transcription factor jun-D
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
JUND	Bos taurus	517192
JUND	Canis lupus familiaris	609409
jund	Danio rerio	564873
JUND	Homo sapiens	3727
Jund	Mus musculus	16478
Jund	Rattus norvegicus	24518

[HomoloGene icon]

HomoloGene homology group 3910

AF_000861

HGK5 | HLK3 | HPCN3 | HUKIII | KCNA3 | KV1.3 | Kv1.3 | MK3 | MK3, MOUSE, HOMOLOG OF | PCN3 | POTASSIUM CHANNEL 3 | potassium channel 3 | POTASSIUM CHANNEL, VOLTAGE-GATED, SHAKER-RELATED SUBFAMILY, MEMBER 3 | potassium voltage-gated channel subfamily A member 3 | potassium voltage-gated channel, shaker-related subfamily, member 3 | type n potassium channel | voltage-gated K(+) channel HuKIII | voltage-gated potassium channel protein Kv1.3 | voltage-gated potassium channel subunit Kv1.3
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
KCNA3	Bos taurus	525507
KCNA3	Canis lupus familiaris	490110
KCNA3	Gallus gallus	404303
KCNA3	Homo sapiens	3738
KCNA3	Macaca mulatta	702245
Kcna3	Mus musculus	16491
KCNA3	Pan troglodytes	469412
Kcna3	Rattus norvegicus	29731

[HomoloGene icon]

HomoloGene homology group 128570

AF_000605

Kca1-3 | Kcna3 | Kv1.3 | Mk-3 | MK3 | potassium voltage gated channel, shaker related subfamily, member 3 | potassium voltage-gated channel subfamily A member 3 | potassium voltage-gated channel, shaker-related subfamily, member 3 | Voltage-gated potassium channel protein Kv1.3 (RGK5) (RCK3) (KV3) | voltage-gated potassium channel subunit Kv1.3
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
KCNA3	Bos taurus	525507
KCNA3	Canis lupus familiaris	490110
KCNA3	Gallus gallus	404303
KCNA3	Homo sapiens	3738
KCNA3	Macaca mulatta	702245
Kcna3	Mus musculus	16491
KCNA3	Pan troglodytes	469412
Kcna3	Rattus norvegicus	29731

[HomoloGene icon]

HomoloGene homology group 128570

AF_000925

Saccharomyces cerevisiae

alpha-ketoglutarate dehydrogenase KGD1 | KGD1 | Kgd1p | OGD1 | YIL125W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP006366	Anopheles gambiae	1276976
AGOS_AER374C	Eremothecium gossypii	4621446
AT3G55410.1	Arabidopsis thaliana	824707
AT5G65750.1	Arabidopsis thaliana	836704
KGD1	Saccharomyces cerevisiae	854681
kgd1	Schizosaccharomyces pombe	2540991
KLLA0F04477g	Kluyveromyces lactis	2894978
MGG_12767	Magnaporthe oryzae	5050140
Nc73EF	Drosophila melanogaster	39899
NCU05425	Neurospora crassa	3879396
OGDH	Bos taurus	534599
OGDH	Canis lupus familiaris	475499
OGDH	Gallus gallus	426429
OGDH	Homo sapiens	4967
OGDH	Macaca mulatta	698854
Ogdh	Mus musculus	18293
OGDH	Pan troglodytes	738474
Ogdh	Rattus norvegicus	360975
ogdha	Danio rerio	564552
ogdhb	Danio rerio	797715
Os04g0390000	Oryza sativa	4335673
Os07g0695800	Oryza sativa	4344403
T22B11.5	Caenorhabditis elegans	177235

[HomoloGene icon]

HomoloGene homology group 55662

AF_000874

alpha-kl | Kl | klotho | secreted form of Klotho protein
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
KL	Bos taurus	784635
KL	Canis lupus familiaris	100685604
KL	Gallus gallus	418909
KL	Homo sapiens	9365
Kl	Mus musculus	16591
KL	Pan troglodytes	467257
Kl	Rattus norvegicus	83504
LOC562316	Danio rerio	562316
LOC714042	Macaca mulatta	714042

[HomoloGene icon]

HomoloGene homology group 68415

AF_000941

Saccharomyces cerevisiae

LAG1 | Lag1p | sphingosine N-acyltransferase LAG1 | YHL003C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_ABR009W	Eremothecium gossypii	4619047
KLLA0B13497g	Kluyveromyces lactis	2897412
LAC1	Saccharomyces cerevisiae	853861
lac1	Schizosaccharomyces pombe	2540466
LAG1	Saccharomyces cerevisiae	856386
MGG_05189	Magnaporthe oryzae	2675700
NCU00008	Neurospora crassa	3873171

[HomoloGene icon]

HomoloGene homology group 101614

AF_001012

Saccharomyces cerevisiae

LSB1 | Lsb1p | YGR136W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
KLLA0E03873g	Kluyveromyces lactis	2893877
LSB1	Saccharomyces cerevisiae	853037
MGG_02835	Magnaporthe oryzae	2682388
NCU00696	Neurospora crassa	3881898
PIN3	Saccharomyces cerevisiae	856277
SPBC119.05c	Schizosaccharomyces pombe	2539945

[HomoloGene icon]

HomoloGene homology group 39131

AF_001078

FK506 binding protein 12-rapamycin associated protein 1 | FK506 binding protein 12-rapamycin associated protein 2 | FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1 | FK506-binding protein 12-rapamycin complex-associated protein 1 | FKBP-rapamycin associated protein | FKBP12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1 | FKBP12-rapamycin complex-associated protein 1 | FLJ44809 | FRAP | FRAP1 | FRAP2 | MAMMALIAN TARGET OF RAPAMYCIN | mammalian target of rapamycin | mechanistic target of rapamycin (serine/threonine kinase) | MTOR | RAFT1 | rapamycin and FKBP12 target 1 | rapamycin associated protein FRAP2 | rapamycin target protein | rapamycin target protein 1 | RAPT1 | serine/threonine-protein kinase mTOR
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP007873	Anopheles gambiae	1278082
AGOS_AFR420W	Eremothecium gossypii	4622240
KLLA0B13948g	Kluyveromyces lactis	2897414
MTOR	Bos taurus	100139219
MTOR	Canis lupus familiaris	478232
mtor	Danio rerio	324254
MTOR	Gallus gallus	419455
MTOR	Homo sapiens	2475
Mtor	Mus musculus	56717
Mtor	Rattus norvegicus	56718
Os05g0235300	Oryza sativa	4338174
TOR	Arabidopsis thaliana	841427
Tor	Drosophila melanogaster	47396
tor1	Schizosaccharomyces pombe	2540473
TOR2	Saccharomyces cerevisiae	853632

[HomoloGene icon]

HomoloGene homology group 3637

AF_000272

IGF-dependent IGFBP-4 protease | IGFBP-4ase | insulin-like growth factor-dependent IGF-binding protein 4 protease | PAG1 | PAPP-A | Pappa | pappalysin-1 | pregnancy-associated plasma protein A
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
LOC100004323	Danio rerio	100004323
PAPPA	Bos taurus	282647
PAPPA	Canis lupus familiaris	481692
PAPPA	Gallus gallus	417245
PAPPA	Homo sapiens	5069
PAPPA	Macaca mulatta	706783
Pappa	Mus musculus	18491
PAPPA	Pan troglodytes	464690
Pappa	Rattus norvegicus	313262

[HomoloGene icon]

HomoloGene homology group 31097

AF_000758

L-isoaspartyl protein carboxyl methyltransferase | L-ISOASPARTYL/D-ASPARTYL PROTEIN METHYLTRANSFERASE | PCMT1 | PIMT | PROTEIN CARBOXYL METHYLTRANSFERASE 1 | protein L-isoaspartyl/D-aspartyl methyltransferase | protein-beta-aspartate methyltransferase | protein-L-isoaspartate (D-aspartate) O-methyltransferase | protein-L-isoaspartate(D-aspartate) O-methyltransferase
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AT5G50240.1	Arabidopsis thaliana	835089
MGG_03476	Magnaporthe oryzae	2676825
NCU05078	Neurospora crassa	3872214
pcm-1	Caenorhabditis elegans	178981
pcm2	Schizosaccharomyces pombe	2543383
pcmt	Danio rerio	30751
PCMT1	Bos taurus	613854
PCMT1	Canis lupus familiaris	476242
PCMT1	Gallus gallus	428607
PCMT1	Homo sapiens	5110
PCMT1	Macaca mulatta	695893
Pcmt1	Mus musculus	18537
PCMT1	Pan troglodytes	463062
Pcmt1	Rattus norvegicus	25604

[HomoloGene icon]

HomoloGene homology group 55895

AF_000948

Saccharomyces cerevisiae

G8561 | PHB2 | Phb2p | YGR231C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009642	Anopheles gambiae	1279019
AGOS_ADL141W	Eremothecium gossypii	4620097
KLLA0E15731g	Kluyveromyces lactis	2894473
l(2)03709	Drosophila melanogaster	46038
MGG_09886	Magnaporthe oryzae	2680930
NCU03310	Neurospora crassa	3880636
Os03g0841700	Oryza sativa	4334737
Os07g0262200	Oryza sativa	4342874
phb-2	Caenorhabditis elegans	174034
PHB1	Arabidopsis thaliana	828969
PHB2	Arabidopsis thaliana	839228
PHB2	Bos taurus	515363
PHB2	Canis lupus familiaris	486716
phb2	Danio rerio	324421
PHB2	Gallus gallus	771124
PHB2	Homo sapiens	11331
PHB2	Macaca mulatta	714693
Phb2	Mus musculus	12034
PHB2	Pan troglodytes	451805
Phb2	Rattus norvegicus	114766
PHB2	Saccharomyces cerevisiae	853146
phb2	Schizosaccharomyces pombe	2538888
PHB6	Arabidopsis thaliana	816575
PHB7	Arabidopsis thaliana	834437
zgc:86841	Danio rerio	436954

[HomoloGene icon]

HomoloGene homology group 5263

AF_000366

Saccharomyces cerevisiae

LDB15 | P7102.18A | PHO85 | Pho85p | phoU | SSG3 | YPL031C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP005772	Anopheles gambiae	1276441
AGOS_AGL242C	Eremothecium gossypii	4622718
cdk-5	Caenorhabditis elegans	176774
CDK5	Bos taurus	281066
CDK5	Canis lupus familiaris	475537
cdk5	Danio rerio	65234
Cdk5	Drosophila melanogaster	36727
CDK5	Gallus gallus	100190948
CDK5	Homo sapiens	1020
CDK5	Macaca mulatta	714445
Cdk5	Mus musculus	12568
CDK5	Pan troglodytes	463891
Cdk5	Rattus norvegicus	140908
KLLA0D11990g	Kluyveromyces lactis	2893430
MGG_04660	Magnaporthe oryzae	2678137
NCU07580	Neurospora crassa	3874421
pef1	Schizosaccharomyces pombe	2539366
PHO85	Saccharomyces cerevisiae	856076

[HomoloGene icon]

HomoloGene homology group 3623

AF_001024

GRB1 | p85 | p85-ALPHA | phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha | phosphatidylinositol 3-kinase regulatory subunit alpha | PHOSPHATIDYLINOSITOL 3-KINASE, REGULATORY SUBUNIT 1 | PHOSPHATIDYLINOSITOL 3-KINASE, REGULATORY SUBUNIT, 85-KD, ALPHA | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | phosphatidylinositol 3-kinase-associated p-85 alpha | PHOSPHATIDYLINOSITOL 3-KINASE-ASSOCIATED p85-ALPHA | phosphoinositide-3-kinase regulatory subunit | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | PI3-kinase subunit p85-alpha | PI3K regulatory subunit alpha | PIK3R1 | ptdIns-3-kinase regulatory subunit alpha
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
aap-1	Caenorhabditis elegans	172141
PIK3R1	Bos taurus	282307
PIK3R1	Canis lupus familiaris	487235
pik3r1	Danio rerio	557176
PIK3R1	Gallus gallus	427171
PIK3R1	Homo sapiens	5295
PIK3R1	Macaca mulatta	698996
Pik3r1	Mus musculus	18708
PIK3R1	Pan troglodytes	461836
Pik3r1	Rattus norvegicus	25513

[HomoloGene icon]

HomoloGene homology group 7889

AF_000455

Saccharomyces cerevisiae

LSB2 | PIN3 | Pin3p | YPR154W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
KLLA0E03873g	Kluyveromyces lactis	2893877
LSB1	Saccharomyces cerevisiae	853037
MGG_02835	Magnaporthe oryzae	2682388
NCU00696	Neurospora crassa	3881898
PIN3	Saccharomyces cerevisiae	856277
SPBC119.05c	Schizosaccharomyces pombe	2539945

[HomoloGene icon]

HomoloGene homology group 39131

AF_001079

dw | dwarf | GHF-1 | growth hormone factor 1 | Hmp1 | Pit-1 | Pit1 | Pit1-rs1 | pituitary specific transcription factor 1, related sequence 1 | pituitary-specific positive transcription factor 1 | pituitary-specific positive transcription factor 1 variant w | POU domain, class 1, transcription factor 1 | POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) | Pou1f1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
POU1F1	Bos taurus	282315
POU1F1	Canis lupus familiaris	403753
pou1f1	Danio rerio	405777
POU1F1	Gallus gallus	374215
POU1F1	Homo sapiens	5449
POU1F1	Macaca mulatta	719349
Pou1f1	Mus musculus	18736
POU1F1	Pan troglodytes	470861
Pou1f1	Rattus norvegicus	25517

[HomoloGene icon]

HomoloGene homology group 259

AF_000402

Saccharomyces cerevisiae

LPB9 | RAD1 | Rad1p | YPL022W
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP002805	Anopheles gambiae	1273157
AGOS_AFR456C	Eremothecium gossypii	4622280
ERCC4	Bos taurus	516371
ERCC4	Canis lupus familiaris	479842
ercc4	Danio rerio	327322
ERCC4	Gallus gallus	416420
ERCC4	Homo sapiens	2072
ERCC4	Macaca mulatta	712641
Ercc4	Mus musculus	50505
ERCC4	Pan troglodytes	453935
Ercc4	Rattus norvegicus	304719
KLLA0D12210g	Kluyveromyces lactis	2892986
mei-9	Drosophila melanogaster	31373
MGG_02804	Magnaporthe oryzae	2682357
NCU07440	Neurospora crassa	3880767
Os03g0100400	Oryza sativa	4331279
RAD1	Saccharomyces cerevisiae	856085
rad16	Schizosaccharomyces pombe	2538760
UVH1	Arabidopsis thaliana	834117

[HomoloGene icon]

HomoloGene homology group 3836

AF_001070

Saccharomyces cerevisiae

ERC11 | FEN1 | RAD27 | Rad27p | RTH1 | YKL113C | YKL510
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP011448	Anopheles gambiae	1278246
crn-1	Caenorhabditis elegans	171917
FEN1	Arabidopsis thaliana	832721
FEN1	Bos taurus	616242
FEN1	Canis lupus familiaris	476063
Fen1	Drosophila melanogaster	36887
FEN1	Gallus gallus	769677
FEN1	Homo sapiens	2237
FEN1	Macaca mulatta	722348
Fen1	Mus musculus	14156
FEN1	Pan troglodytes	451242
Fen1	Rattus norvegicus	84490
KLLA0F02992g	Kluyveromyces lactis	2895779
MGG_03419	Magnaporthe oryzae	2676517
NCU10776	Neurospora crassa	5847646
Os05g0540100	Oryza sativa	4339464
rad2	Schizosaccharomyces pombe	2543164
RAD27	Saccharomyces cerevisiae	853747

[HomoloGene icon]

HomoloGene homology group 3034

AF_000129

Saccharomyces cerevisiae

L13A | L13e | ribosomal 60S subunit protein L13A | RPL13A | Rpl13ap | YDL082W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP001805	Anopheles gambiae	1281310
AGOS_ADR257C	Eremothecium gossypii	4620515
BBC1	Arabidopsis thaliana	824062
Gm10071	Mus musculus	100040416
KLLA0E22001g	Kluyveromyces lactis	2894438
LOC700603	Macaca mulatta	700603
MGG_09769	Magnaporthe oryzae	5051792
MGG_13645	Magnaporthe oryzae	2680716
NCU05554	Neurospora crassa	3876663
Os03g0576700	Oryza sativa	4333306
Os06g0115500	Oryza sativa	4339923
rpl-13	Caenorhabditis elegans	171949
RPL13	Bos taurus	508221
RPL13	Canis lupus familiaris	479612
rpl13	Danio rerio	378961
RpL13	Drosophila melanogaster	34329
RPL13	Gallus gallus	395849
RPL13	Homo sapiens	6137
Rpl13	Mus musculus	270106
RPL13	Pan troglodytes	454316
Rpl13	Rattus norvegicus	81765
rpl13	Schizosaccharomyces pombe	2543553
RPL13A	Saccharomyces cerevisiae	851477
RPL13B	Saccharomyces cerevisiae	855173
RPL13D	Arabidopsis thaliana	832455

[HomoloGene icon]

HomoloGene homology group 5568

AF_000957

Saccharomyces cerevisiae

L13B | L13e | ribosomal 60S subunit protein L13B | RPL13 | RPL13B | Rpl13bp | YM9375.11C | YMR142C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP001805	Anopheles gambiae	1281310
AGOS_ADR257C	Eremothecium gossypii	4620515
BBC1	Arabidopsis thaliana	824062
Gm10071	Mus musculus	100040416
KLLA0E22001g	Kluyveromyces lactis	2894438
LOC700603	Macaca mulatta	700603
MGG_09769	Magnaporthe oryzae	5051792
MGG_13645	Magnaporthe oryzae	2680716
NCU05554	Neurospora crassa	3876663
Os03g0576700	Oryza sativa	4333306
Os06g0115500	Oryza sativa	4339923
rpl-13	Caenorhabditis elegans	171949
RPL13	Bos taurus	508221
RPL13	Canis lupus familiaris	479612
rpl13	Danio rerio	378961
RpL13	Drosophila melanogaster	34329
RPL13	Gallus gallus	395849
RPL13	Homo sapiens	6137
Rpl13	Mus musculus	270106
RPL13	Pan troglodytes	454316
Rpl13	Rattus norvegicus	81765
rpl13	Schizosaccharomyces pombe	2543553
RPL13A	Saccharomyces cerevisiae	851477
RPL13B	Saccharomyces cerevisiae	855173
RPL13D	Arabidopsis thaliana	832455

[HomoloGene icon]

HomoloGene homology group 5568

AF_000959

Saccharomyces cerevisiae

L21A | L21e | ribosomal 60S subunit protein L21A | RPL21A | Rpl21ap | URP1 | YBR1401 | YBR191W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_AEL254W	Eremothecium gossypii	4620789
KLLA0E23651g	Kluyveromyces lactis	2894367
LOC452503	Pan troglodytes	452503
LOC463812	Pan troglodytes	463812
LOC703876	Macaca mulatta	703876
LOC741910	Pan troglodytes	741910
MGG_02953	Magnaporthe oryzae	2682506
NCU01948	Neurospora crassa	3880381
RPL21	Bos taurus	326584
RPL21	Canis lupus familiaris	607633
rpl21	Danio rerio	336568
RPL21	Gallus gallus	418933
RPL21	Homo sapiens	6144
Rpl21	Mus musculus	19933
Rpl21	Rattus norvegicus	79449
rpl2101	Schizosaccharomyces pombe	2540950
RPL21A	Saccharomyces cerevisiae	852489
RPL21B	Saccharomyces cerevisiae	856026
rpl21b	Schizosaccharomyces pombe	2543337

[HomoloGene icon]

HomoloGene homology group 128048

AF_000976

Saccharomyces cerevisiae

L21B | L21e | LPF6W | ribosomal 60S subunit protein L21B | RPL21B | Rpl21bp | YPL079W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_AEL254W	Eremothecium gossypii	4620789
KLLA0E23651g	Kluyveromyces lactis	2894367
LOC452503	Pan troglodytes	452503
LOC463812	Pan troglodytes	463812
LOC703876	Macaca mulatta	703876
LOC741910	Pan troglodytes	741910
MGG_02953	Magnaporthe oryzae	2682506
NCU01948	Neurospora crassa	3880381
RPL21	Bos taurus	326584
RPL21	Canis lupus familiaris	607633
rpl21	Danio rerio	336568
RPL21	Gallus gallus	418933
RPL21	Homo sapiens	6144
Rpl21	Mus musculus	19933
Rpl21	Rattus norvegicus	79449
rpl2101	Schizosaccharomyces pombe	2540950
RPL21A	Saccharomyces cerevisiae	852489
RPL21B	Saccharomyces cerevisiae	856026
rpl21b	Schizosaccharomyces pombe	2543337

[HomoloGene icon]

HomoloGene homology group 128048

AF_000977

Saccharomyces cerevisiae

L34A | L34e | ribosomal 60S subunit protein L34A | RPL34A | Rpl34ap | YER056BC | YER056C-A
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009324	Anopheles gambiae	1271236
AGOS_ADL078C	Eremothecium gossypii	4620160
AT1G26880	Arabidopsis thaliana	838331
Gm6404	Mus musculus	623174
KLLA0C08371g	Kluyveromyces lactis	2892551
LOC100685685	Canis lupus familiaris	100685685
LOC422526	Gallus gallus	422526
LOC696636	Macaca mulatta	696636
LOC697758	Macaca mulatta	697758
LOC702677	Macaca mulatta	702677
MGG_05296	Magnaporthe oryzae	2675763
NCU07857	Neurospora crassa	3879257
Os08g0156800	Oryza sativa	4344696
Os08g0436800	Oryza sativa	4345669
rpl-34	Caenorhabditis elegans	178173
RPL34	Arabidopsis thaliana	843298
rpl34	Danio rerio	394097
RPL34	Homo sapiens	6164
RPL34	Pan troglodytes	461427
rpl3401	Schizosaccharomyces pombe	2541989
RpL34a	Drosophila melanogaster	43169
RPL34A	Saccharomyces cerevisiae	856784
RpL34b	Drosophila melanogaster	41120
RPL34B	Saccharomyces cerevisiae	854759
rpl34b	Schizosaccharomyces pombe	2538815
RPL34C	Arabidopsis thaliana	822524
Rpl34l1	Rattus norvegicus	296870

[HomoloGene icon]

HomoloGene homology group 105146

AF_000988

Saccharomyces cerevisiae

L34B | L34e | ribosomal 60S subunit protein L34B | RPL34B | Rpl34bp | YIL052C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009324	Anopheles gambiae	1271236
AGOS_ADL078C	Eremothecium gossypii	4620160
AT1G26880	Arabidopsis thaliana	838331
Gm6404	Mus musculus	623174
KLLA0C08371g	Kluyveromyces lactis	2892551
LOC100685685	Canis lupus familiaris	100685685
LOC422526	Gallus gallus	422526
LOC696636	Macaca mulatta	696636
LOC697758	Macaca mulatta	697758
LOC702677	Macaca mulatta	702677
MGG_05296	Magnaporthe oryzae	2675763
NCU07857	Neurospora crassa	3879257
Os08g0156800	Oryza sativa	4344696
Os08g0436800	Oryza sativa	4345669
rpl-34	Caenorhabditis elegans	178173
RPL34	Arabidopsis thaliana	843298
rpl34	Danio rerio	394097
RPL34	Homo sapiens	6164
RPL34	Pan troglodytes	461427
rpl3401	Schizosaccharomyces pombe	2541989
RpL34a	Drosophila melanogaster	43169
RPL34A	Saccharomyces cerevisiae	856784
RpL34b	Drosophila melanogaster	41120
RPL34B	Saccharomyces cerevisiae	854759
rpl34b	Schizosaccharomyces pombe	2538815
RPL34C	Arabidopsis thaliana	822524
Rpl34l1	Rattus norvegicus	296870

[HomoloGene icon]

HomoloGene homology group 105146

AF_000989

Saccharomyces cerevisiae

L37A | L37e | L43 | L9470.6 | ribosomal 60S subunit protein L37A | RPL35A | RPL37A | Rpl37ap | YL35 | YLR185W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP000952	Anopheles gambiae	1270447
AGOS_AFR688C	Eremothecium gossypii	4622525
AT1G15250	Arabidopsis thaliana	838092
AT1G52300	Arabidopsis thaliana	841660
AT3G16080	Arabidopsis thaliana	820853
KLLA0C01870g	Kluyveromyces lactis	2892544
LOC100360654	Rattus norvegicus	100360654
LOC712599	Macaca mulatta	712599
MGG_02620	Magnaporthe oryzae	2682819
NCU01966	Neurospora crassa	3880495
Os02g0111700	Oryza sativa	4328048
Os02g0815001	Oryza sativa	9267955
Os08g0128500	Oryza sativa	4344579
rpl-37	Caenorhabditis elegans	175460
rpl3702	Schizosaccharomyces pombe	2538715
rpl3703	Schizosaccharomyces pombe	3361407
RpL37a	Drosophila melanogaster	32446
RPL37A	Saccharomyces cerevisiae	850882
RPL37B	Saccharomyces cerevisiae	852111
W01D2.1	Caenorhabditis elegans	175141

[HomoloGene icon]

HomoloGene homology group 68110

AF_000992

Saccharomyces cerevisiae

L17A | L6A | L6e | ribosomal 60S subunit protein L6A | rp18 | RPL17A | RPL6A | Rpl6ap | YL16 | YL16A | YML073C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP001911	Anopheles gambiae	1281215
AGOS_AER149W	Eremothecium gossypii	4621214
Gm5428	Mus musculus	432502
KLLA0B04686g	Kluyveromyces lactis	2897480
LOC712820	Macaca mulatta	712820
LOC737972	Pan troglodytes	737972
MGG_04444	Magnaporthe oryzae	2677964
NCU02707	Neurospora crassa	3881630
Os02g0591700	Oryza sativa	4329831
Os04g0473400	Oryza sativa	4336140
rpl-6	Caenorhabditis elegans	176015
RPL6	Bos taurus	511051
RPL6	Canis lupus familiaris	403691
rpl6	Danio rerio	336727
RpL6	Drosophila melanogaster	43723
RPL6	Gallus gallus	373957
RPL6	Homo sapiens	6128
RPL6	Macaca mulatta	712133
Rpl6	Mus musculus	19988
Rpl6	Rattus norvegicus	117042
rpl6	Schizosaccharomyces pombe	2539372
RPL6A	Arabidopsis thaliana	838435
RPL6A	Saccharomyces cerevisiae	854902
RPL6B	Arabidopsis thaliana	843746
RPL6B	Saccharomyces cerevisiae	851169
RPL6C	Arabidopsis thaliana	843744

[HomoloGene icon]

HomoloGene homology group 31001

AF_000967

Saccharomyces cerevisiae

L17B | L6B | L6e | L9324.4 | ribosomal 60S subunit protein L6B | rp18 | RPL16B | RPL17B | RPL6B | Rpl6bp | YL16 | YL16B | YLR448W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP001911	Anopheles gambiae	1281215
AGOS_AER149W	Eremothecium gossypii	4621214
Gm5428	Mus musculus	432502
KLLA0B04686g	Kluyveromyces lactis	2897480
LOC712820	Macaca mulatta	712820
LOC737972	Pan troglodytes	737972
MGG_04444	Magnaporthe oryzae	2677964
NCU02707	Neurospora crassa	3881630
Os02g0591700	Oryza sativa	4329831
Os04g0473400	Oryza sativa	4336140
rpl-6	Caenorhabditis elegans	176015
RPL6	Bos taurus	511051
RPL6	Canis lupus familiaris	403691
rpl6	Danio rerio	336727
RpL6	Drosophila melanogaster	43723
RPL6	Gallus gallus	373957
RPL6	Homo sapiens	6128
RPL6	Macaca mulatta	712133
Rpl6	Mus musculus	19988
Rpl6	Rattus norvegicus	117042
rpl6	Schizosaccharomyces pombe	2539372
RPL6A	Arabidopsis thaliana	838435
RPL6A	Saccharomyces cerevisiae	854902
RPL6B	Arabidopsis thaliana	843746
RPL6B	Saccharomyces cerevisiae	851169
RPL6C	Arabidopsis thaliana	843744

[HomoloGene icon]

HomoloGene homology group 31001

AF_000968

Saccharomyces cerevisiae

L30 | L6A | L7A | ribosomal 60S subunit protein L7A | rp11 | RPL6A | RPL7A | Rpl7ap | RPL8A | YGL076C | YL8 | YL8A
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP008916	Anopheles gambiae	1279884
AGOS_AFL082W	Eremothecium gossypii	4621694
AT2G01250	Arabidopsis thaliana	814652
AT2G44120	Arabidopsis thaliana	819018
AT3G13580	Arabidopsis thaliana	820560
KLLA0D03410g	Kluyveromyces lactis	2892731
MGG_05237	Magnaporthe oryzae	2675441
NCU07829	Neurospora crassa	3879098
Os04g0605900	Oryza sativa	4336914
Os08g0234000	Oryza sativa	4345009
rpl-7	Caenorhabditis elegans	171602
RPL7	Bos taurus	514966
RPL7	Canis lupus familiaris	477912
rpl7	Danio rerio	336710
RpL7	Drosophila melanogaster	34352
RPL7	Gallus gallus	420182
RPL7	Homo sapiens	6129
RPL7	Macaca mulatta	698049
Rpl7	Mus musculus	19989
RPL7	Pan troglodytes	464232
Rpl7	Rattus norvegicus	297755
rpl701	Schizosaccharomyces pombe	2540841
rpl702	Schizosaccharomyces pombe	2543448
RPL7A	Saccharomyces cerevisiae	852804
RPL7B	Saccharomyces cerevisiae	855903

[HomoloGene icon]

HomoloGene homology group 87772

AF_000985

Saccharomyces cerevisiae

L30 | L6B | L7B | ribosomal 60S subunit protein L7B | rp11 | RPL6B | RPL7B | Rpl7bp | YL8 | YL8B | YPL198W
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP008916	Anopheles gambiae	1279884
AGOS_AFL082W	Eremothecium gossypii	4621694
AT2G01250	Arabidopsis thaliana	814652
AT2G44120	Arabidopsis thaliana	819018
AT3G13580	Arabidopsis thaliana	820560
KLLA0D03410g	Kluyveromyces lactis	2892731
MGG_05237	Magnaporthe oryzae	2675441
NCU07829	Neurospora crassa	3879098
Os04g0605900	Oryza sativa	4336914
Os08g0234000	Oryza sativa	4345009
rpl-7	Caenorhabditis elegans	171602
RPL7	Bos taurus	514966
RPL7	Canis lupus familiaris	477912
rpl7	Danio rerio	336710
RpL7	Drosophila melanogaster	34352
RPL7	Gallus gallus	420182
RPL7	Homo sapiens	6129
RPL7	Macaca mulatta	698049
Rpl7	Mus musculus	19989
RPL7	Pan troglodytes	464232
Rpl7	Rattus norvegicus	297755
rpl701	Schizosaccharomyces pombe	2540841
rpl702	Schizosaccharomyces pombe	2543448
RPL7A	Saccharomyces cerevisiae	852804
RPL7B	Saccharomyces cerevisiae	855903

[HomoloGene icon]

HomoloGene homology group 87772

AF_000986

Saccharomyces cerevisiae

L4A | L8A | L8e | MAK7 | ribosomal 60S subunit protein L8A | rp6 | RPL4A | RPL8A | Rpl8ap | YHL033C | YL5
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_ACL070C	Eremothecium gossypii	4619454
AT2G47610	Arabidopsis thaliana	819374
AT3G62870	Arabidopsis thaliana	825462
MGG_04612	Magnaporthe oryzae	2677998
NCU04779	Neurospora crassa	3876375
Os08g0326400	Oryza sativa	4345279
Os09g0507800	Oryza sativa	4347522
RL7A_ANOGA	Anopheles gambiae	1276631
rpl-7A	Caenorhabditis elegans	177203
RPL7A	Bos taurus	513128
RPL7A	Canis lupus familiaris	403678
rpl7a	Danio rerio	337010
RpL7A	Drosophila melanogaster	31588
RPL7A	Gallus gallus	417158
RPL7A	Homo sapiens	6130
RPL7A	Macaca mulatta	722215
Rpl7a	Mus musculus	27176
Rpl7a	Rattus norvegicus	296596
rpl8	Schizosaccharomyces pombe	2540517
RPL8A	Saccharomyces cerevisiae	856352
RPL8B	Saccharomyces cerevisiae	850682

[HomoloGene icon]

HomoloGene homology group 105462

AF_000994

Saccharomyces cerevisiae

KRB1 | L4B | L8B | L8e | ribosomal 60S subunit protein L8B | rp6 | RPL4B | RPL8B | Rpl8bp | SCL41 | YL5 | YLL045C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_ACL070C	Eremothecium gossypii	4619454
AT2G47610	Arabidopsis thaliana	819374
AT3G62870	Arabidopsis thaliana	825462
MGG_04612	Magnaporthe oryzae	2677998
NCU04779	Neurospora crassa	3876375
Os08g0326400	Oryza sativa	4345279
Os09g0507800	Oryza sativa	4347522
RL7A_ANOGA	Anopheles gambiae	1276631
rpl-7A	Caenorhabditis elegans	177203
RPL7A	Bos taurus	513128
RPL7A	Canis lupus familiaris	403678
rpl7a	Danio rerio	337010
RpL7A	Drosophila melanogaster	31588
RPL7A	Gallus gallus	417158
RPL7A	Homo sapiens	6130
RPL7A	Macaca mulatta	722215
Rpl7a	Mus musculus	27176
Rpl7a	Rattus norvegicus	296596
rpl8	Schizosaccharomyces pombe	2540517
RPL8A	Saccharomyces cerevisiae	856352
RPL8B	Saccharomyces cerevisiae	850682

[HomoloGene icon]

HomoloGene homology group 105462

AF_000921

Saccharomyces cerevisiae

L6 | L8B | L9B | N2406 | ribosomal 60S subunit protein L9B | rp24 | RPL8B | RPL9B | Rpl9bp | YL11 | YNL067W | YNL2406W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009508	Anopheles gambiae	1271403
AGOS_ADL290W	Eremothecium gossypii	4619941
AT1G33120	Arabidopsis thaliana	840208
KLLA0E09109g	Kluyveromyces lactis	2894230
KLLA0F04499g	Kluyveromyces lactis	2894979
LOC718478	Macaca mulatta	718478
MGG_04829	Magnaporthe oryzae	2678056
NCU02744	Neurospora crassa	3881278
Os02g0103700	Oryza sativa	4327999
Os09g0485900	Oryza sativa	4347422
PGY2	Arabidopsis thaliana	840211
rpl-9	Caenorhabditis elegans	176071
RPL9	Bos taurus	282884
RPL9	Canis lupus familiaris	479109
rpl9	Danio rerio	336702
RpL9	Drosophila melanogaster	34526
RPL9	Gallus gallus	425468
RPL9	Homo sapiens	6133
Rpl9	Mus musculus	20005
RPL9	Pan troglodytes	737526
RPL9A	Saccharomyces cerevisiae	852730
rpl9a	Schizosaccharomyces pombe	2543380
RPL9B	Saccharomyces cerevisiae	855658
rpl9b	Schizosaccharomyces pombe	2539464
RPL9D	Arabidopsis thaliana	826637

[HomoloGene icon]

HomoloGene homology group 90855

AF_000995

Saccharomyces cerevisiae

L2118 | NAB1B | NAB4 | ribosomal 40S subunit protein S0B | RPS0B | Rps0bp | S0B | S2 | YLR048W | YST2
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_ACL140C	Eremothecium gossypii	4619384
KLLA0E16171g	Kluyveromyces lactis	2893732
LOC701691	Macaca mulatta	701691
LOC741646	Pan troglodytes	741646
MGG_11776	Magnaporthe oryzae	5049564
NCU03393	Neurospora crassa	3872987
rps002	Schizosaccharomyces pombe	2543293
RPS0A	Saccharomyces cerevisiae	853128
rps0a	Schizosaccharomyces pombe	2541144
RPS0B	Saccharomyces cerevisiae	850737

[HomoloGene icon]

HomoloGene homology group 88770

AF_000971

Saccharomyces cerevisiae

L9753.9 | PLC1 | ribosomal 40S subunit protein S1A | RP10A | rp10A | RPS10A | RPS1A | Rps1ap | S1A | S1e | YLR441C
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AGOS_AER131C	Eremothecium gossypii	4621196
AT3G04840	Arabidopsis thaliana	819644
AT4G34670	Arabidopsis thaliana	829619
KLLA0B05060g	Kluyveromyces lactis	2897271
LOC711043	Macaca mulatta	711043
MGG_06919	Magnaporthe oryzae	2685092
NCU01452	Neurospora crassa	3872112
Os02g0287000	Oryza sativa	4329042
Os03g0200500	Oryza sativa	4331966
Os12g0406200	Oryza sativa	4352048
rps-1	Caenorhabditis elegans	175584
rps101	Schizosaccharomyces pombe	2542817
rps102	Schizosaccharomyces pombe	2541737
RPS1A	Saccharomyces cerevisiae	851162
RPS1B	Saccharomyces cerevisiae	854939
RPS3A	Bos taurus	282053
RPS3A	Canis lupus familiaris	403677
rps3a	Danio rerio	337240
RpS3A	Drosophila melanogaster	43768
RPS3A	Gallus gallus	422477
RPS3A	Homo sapiens	6189
Rps3a	Mus musculus	20091
RPS3A	Pan troglodytes	461536
Rps3a	Rattus norvegicus	29288
RS3A_ANOGA	Anopheles gambiae	1274189

[HomoloGene icon]

HomoloGene homology group 68112

AF_001010

Saccharomyces cerevisiae

J0664 | ribosomal 40S subunit protein S21B | RPS21B | Rps21bp | RPS25B | RPS26B | S21B | S21e | S26B | YJL136C | YS25
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009431	Anopheles gambiae	1269220
AGOS_ACR255C	Eremothecium gossypii	4619792
KLLA0A05700g	Kluyveromyces lactis	2896593
LOC100363012	Rattus norvegicus	100363012
LOC458388	Pan troglodytes	458388
MGG_06837	Magnaporthe oryzae	2685010
NCU08627	Neurospora crassa	3880995
rps-21	Caenorhabditis elegans	176011
RPS21	Bos taurus	615178
RPS21	Canis lupus familiaris	485959
rps21	Danio rerio	394166
RpS21	Drosophila melanogaster	33487
RPS21	Gallus gallus	419228
RPS21	Homo sapiens	6227
RPS21	Macaca mulatta	699565
Rps21	Mus musculus	66481
RPS21	Pan troglodytes	737911
Rps21	Rattus norvegicus	81775
rps21	Schizosaccharomyces pombe	2540806
RPS21A	Saccharomyces cerevisiae	853931
RPS21B	Saccharomyces cerevisiae	853305

[HomoloGene icon]

HomoloGene homology group 90915

AF_000835

Saccharomyces cerevisiae

J0355 | ribosomal 40S subunit protein S22A | rp50 | RPS22A | Rps22ap | RPS24 | RPS24A | S22A | S24A | S8 | YJL190C | YS22
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP000541	Anopheles gambiae	3289708
AgaP_AGAP009572	Anopheles gambiae	1278933
AGOS_AEL151C	Eremothecium gossypii	4620896
AGOS_AFR579W	Eremothecium gossypii	4622408
AT5G59850	Arabidopsis thaliana	836107
KLLA0B07601g	Kluyveromyces lactis	2896891
KLLA0B07931g	Kluyveromyces lactis	2897329
LOC702174	Macaca mulatta	702174
LOC743847	Pan troglodytes	743847
MGG_06479	Magnaporthe oryzae	2684634
NCU06431	Neurospora crassa	3873491
Os02g0478600	Oryza sativa	4329361
Os07g0208000	Oryza sativa	4342697
rps-22	Caenorhabditis elegans	175338
RPS15A	Arabidopsis thaliana	837291
RPS15A	Bos taurus	337888
RPS15A	Canis lupus familiaris	100683775
rps15a	Danio rerio	336764
RPS15A	Gallus gallus	427675
RPS15A	Homo sapiens	6210
Rps15a	Mus musculus	267019
Rps15a	Rattus norvegicus	117053
RpS15Aa	Drosophila melanogaster	44150
RpS15Ab	Drosophila melanogaster	36142
RPS15AD	Arabidopsis thaliana	823747
rps2201	Schizosaccharomyces pombe	2541838
rps2202	Schizosaccharomyces pombe	2541977
RPS22A	Saccharomyces cerevisiae	853249
RPS22B	Saccharomyces cerevisiae	851082

[HomoloGene icon]

HomoloGene homology group 128982

AF_000830

Saccharomyces cerevisiae

L8039.6 | ribosomal 40S subunit protein S22B | rp50 | RPS22B | Rps22bp | RPS24B | S22B | S24B | S8 | YLR367W | YS22
Source:

Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP000541	Anopheles gambiae	3289708
AgaP_AGAP009572	Anopheles gambiae	1278933
AGOS_AEL151C	Eremothecium gossypii	4620896
AGOS_AFR579W	Eremothecium gossypii	4622408
AT5G59850	Arabidopsis thaliana	836107
KLLA0B07601g	Kluyveromyces lactis	2896891
KLLA0B07931g	Kluyveromyces lactis	2897329
LOC702174	Macaca mulatta	702174
LOC743847	Pan troglodytes	743847
MGG_06479	Magnaporthe oryzae	2684634
NCU06431	Neurospora crassa	3873491
Os02g0478600	Oryza sativa	4329361
Os07g0208000	Oryza sativa	4342697
rps-22	Caenorhabditis elegans	175338
RPS15A	Arabidopsis thaliana	837291
RPS15A	Bos taurus	337888
RPS15A	Canis lupus familiaris	100683775
rps15a	Danio rerio	336764
RPS15A	Gallus gallus	427675
RPS15A	Homo sapiens	6210
Rps15a	Mus musculus	267019
Rps15a	Rattus norvegicus	117053
RpS15Aa	Drosophila melanogaster	44150
RpS15Ab	Drosophila melanogaster	36142
RPS15AD	Arabidopsis thaliana	823747
rps2201	Schizosaccharomyces pombe	2541838
rps2202	Schizosaccharomyces pombe	2541977
RPS22A	Saccharomyces cerevisiae	853249
RPS22B	Saccharomyces cerevisiae	851082

[HomoloGene icon]

HomoloGene homology group 128982

AF_000998

Saccharomyces cerevisiae

ETH10 | L9470.9 | methionine adenosyltransferase SAM1 | SAM1 | Sam1p | YLR180W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009447	Anopheles gambiae	1269245
AGOS_AFR692C	Eremothecium gossypii	4622529
KLLA0C01782g	Kluyveromyces lactis	2892009
MAT2A	Bos taurus	527403
MAT2A	Canis lupus familiaris	475770
MAT2A	Homo sapiens	4144
Mat2a	Mus musculus	232087
MAT2A	Pan troglodytes	459363
Mat2a	Rattus norvegicus	171347
mat2ab	Danio rerio	791612
METK3	Arabidopsis thaliana	818260
MGG_00383	Magnaporthe oryzae	2674392
NCU02657	Neurospora crassa	3881571
Sam-S	Drosophila melanogaster	48552
SAM1	Saccharomyces cerevisiae	850877
sam1	Schizosaccharomyces pombe	2539943
SAM2	Saccharomyces cerevisiae	852113
sams-1	Caenorhabditis elegans	181370
sams-2	Caenorhabditis elegans	178446
sams-3	Caenorhabditis elegans	177355
sams-4	Caenorhabditis elegans	177354
sams-5	Caenorhabditis elegans	177389

[HomoloGene icon]

HomoloGene homology group 38112

AF_000167

histone deacetylase complex subunit Sin3a | KIAA0700 | paired amphipathic helix protein Sin3a | SIN3 homolog A, transcription regulator | SIN3 homolog A, transcription regulator (yeast) | SIN3 transcription regulator homolog A (yeast) | SIN3, YEAST, HOMOLOG OF, A | SIN3A | transcriptional co-repressor Sin3A | transcriptional corepressor Sin3a | transcriptional regulator, SIN3A
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP007892	Anopheles gambiae	1278063
AGOS_ACL004W	Eremothecium gossypii	4619525
KLLA0C06182g	Kluyveromyces lactis	2892627
MGG_13498	Magnaporthe oryzae	2676945
NCU02578	Neurospora crassa	3881859
pst1	Schizosaccharomyces pombe	2540018
SIN3	Saccharomyces cerevisiae	854158
SIN3A	Bos taurus	518504
SIN3A	Canis lupus familiaris	478372
Sin3A	Drosophila melanogaster	36382
SIN3A	Gallus gallus	415307
SIN3A	Homo sapiens	25942
SIN3A	Macaca mulatta	705719
Sin3a	Mus musculus	20466
SIN3A	Pan troglodytes	453759
Sin3a	Rattus norvegicus	363067
sin3aa	Danio rerio	563090
SNL1	Arabidopsis thaliana	821265
SNL2	Arabidopsis thaliana	831354

[HomoloGene icon]

HomoloGene homology group 32124

AF_000879

Saccharomyces cerevisiae

G1155 | SIP2 | Sip2p | SPM2 | YGL208W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
aakb-1	Caenorhabditis elegans	181492
aakb-2	Caenorhabditis elegans	176552
amk2	Schizosaccharomyces pombe	2539130
KINB1	Arabidopsis thaliana	832243
LOC100856379	Canis lupus familiaris	100856379
MGG_06930	Magnaporthe oryzae	2685103
NCU03837	Neurospora crassa	3876743
Os05g0491200	Oryza sativa	4339173
PRKAB2	Bos taurus	512665
prkab2	Danio rerio	100170795
PRKAB2	Gallus gallus	427017
PRKAB2	Homo sapiens	5565
PRKAB2	Macaca mulatta	699806
Prkab2	Mus musculus	108097
PRKAB2	Pan troglodytes	457245
Prkab2	Rattus norvegicus	64562
SIP2	Saccharomyces cerevisiae	852664

[HomoloGene icon]

HomoloGene homology group 38046

AF_000354

hSIR2 | hSIRT1 | HST2, S. CEREVISIAE, HOMOLOG OF | NAD-dependent deacetylase sirtuin-1 | NAD-dependent protein deacetylase sirtuin-1 | regulatory protein SIR2 homolog 1 | RP11-57G10.3 | SIR2, S. CEREVISIAE, HOMOLOG-LIKE 1 | SIR2-ALPHA | sir2-like 1 | SIR2-like protein 1 | SIR2alpha | SIR2L1 | SIRT1 | sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) | sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1 | SIRTUIN 1 | sirtuin 1 | sirtuin type 1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
sir-2.1	Caenorhabditis elegans	177924
SIRT1	Bos taurus	613629
SIRT1	Canis lupus familiaris	489012
sirt1	Danio rerio	797132
SIRT1	Gallus gallus	423646
SIRT1	Homo sapiens	23411
SIRT1	Macaca mulatta	695682
Sirt1	Mus musculus	93759
SIRT1	Pan troglodytes	466088

[HomoloGene icon]

HomoloGene homology group 56556

AF_000670

INDOPHENOL OXIDASE B | indophenoloxidase B | IPO-B | IPOB | MANGANESE SUPEROXIDE DISMUTASE | manganese-containing superoxide dismutase | mangano-superoxide dismutase | Mn superoxide dismutase | MNSOD | MVCD6 | RP1-56L9.2 | SOD2 | SUPEROXIDE DISMUTASE 2 | superoxide dismutase 2, mitochondrial | superoxide dismutase [Mn], mitochondrial | SUPEROXIDE DISMUTASE, MITOCHONDRIAL
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
KLLA0E03609g	Kluyveromyces lactis	2894718
MGG_00212	Magnaporthe oryzae	2674520
MNSOD1	Anopheles gambiae	1275254
NCU09560	Neurospora crassa	3875632
Os05g0323900	Oryza sativa	4338417
sod-2	Caenorhabditis elegans	172632
sod-3	Caenorhabditis elegans	181748
SOD2	Bos taurus	281496
SOD2	Canis lupus familiaris	476258
sod2	Danio rerio	335799
Sod2	Drosophila melanogaster	36878
SOD2	Gallus gallus	374042
SOD2	Homo sapiens	6648
SOD2	Macaca mulatta	574097
Sod2	Mus musculus	20656
SOD2	Pan troglodytes	449634
Sod2	Rattus norvegicus	24787
SOD2	Saccharomyces cerevisiae	856399
sod2	Schizosaccharomyces pombe	2542886
SODA	Arabidopsis thaliana	820263

[HomoloGene icon]

HomoloGene homology group 530

AF_000772

hLKB1 | liver kinase B1 | LKB1 | PJS | polarization-related protein LKB1 | renal carcinoma antigen NY-REN-19 | serine/threonine kinase 11 | serine/threonine kinase 11 (Peutz-Jeghers syndrome) | SERINE/THREONINE PROTEIN KINASE 11 | serine/threonine-protein kinase 11 | serine/threonine-protein kinase LKB1 | serine/threonine-protein kinase STK11 | STK11
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
lkb1	Drosophila melanogaster	41673
par-4	Caenorhabditis elegans	180185
STK11	Canis lupus familiaris	485088
stk11	Danio rerio	550537
STK11	Gallus gallus	420105
STK11	Homo sapiens	6794
STK11	Macaca mulatta	705686
Stk11	Mus musculus	20869
STK11	Pan troglodytes	468641
Stk11	Rattus norvegicus	314621

[HomoloGene icon]

HomoloGene homology group 393

AF_001040

Schizosaccharomyces pombe

hog1 | MAP kinase Sty1 | phh1 | SPAC24B11.06c | spc1 | sty1
Source:

Ageing Phenotype Observation—Data Type 1	GenDR
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP012148	Anopheles gambiae	1280530
AGOS_AGR048C	Eremothecium gossypii	4623013
HOG1	Saccharomyces cerevisiae	850803
KLLA0F20053g	Kluyveromyces lactis	2895492
LOC718976	Macaca mulatta	718976
MAPK14	Bos taurus	534492
MAPK14	Canis lupus familiaris	403856
MAPK14	Gallus gallus	421183
MAPK14	Homo sapiens	1432
Mapk14	Mus musculus	26416
MAPK14	Pan troglodytes	450161
Mapk14	Rattus norvegicus	81649
mapk14a	Danio rerio	65237
MGG_01822	Magnaporthe oryzae	2679641
Mpk2	Drosophila melanogaster	42866
MPK3	Arabidopsis thaliana	823706
NCU07024	Neurospora crassa	3878327
Os03g0285800	Oryza sativa	4332475
p38b	Drosophila melanogaster	34780
pmk-1	Caenorhabditis elegans	191743
sty1	Schizosaccharomyces pombe	2541652

[HomoloGene icon]

HomoloGene homology group 31777

AF_001130

GTF2D | GTF2D1 | HDL4 | RP1-191N21.3 | SCA17 | SCA17 GENE | TATA box binding protein | TATA BOX-BINDING PROTEIN | TATA sequence-binding protein | TATA-box binding protein N-terminal domain | TATA-box factor | TATA-box-binding protein | TBP | TF2D | TFIID | transcription initiation factor TFIID TBP subunit
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP010958	Anopheles gambiae	1271006
AGOS_AGR134W	Eremothecium gossypii	4623102
KLLA0E10099g	Kluyveromyces lactis	2893858
MGG_08878	Magnaporthe oryzae	2679864
NCU04770	Neurospora crassa	3876366
Os10g0432300	Oryza sativa	4348699
SPT15	Saccharomyces cerevisiae	856891
TBP	Bos taurus	516578
TBP	Canis lupus familiaris	611193
tbp	Danio rerio	368882
Tbp	Drosophila melanogaster	37476
TBP	Gallus gallus	395995
TBP	Homo sapiens	6908
TBP	Macaca mulatta	696258
Tbp	Mus musculus	21374
TBP	Pan troglodytes	738472
Tbp	Rattus norvegicus	117526
tbp-1	Caenorhabditis elegans	176054
tbp1	Schizosaccharomyces pombe	2541582

[HomoloGene icon]

HomoloGene homology group 2404

AF_000482

EST2 | TCS1 | telomerase catalytic subunit | telomerase reverse transcriptase | telomerase reverse transcriptase beta | Tert | TP2 | TR | TRT
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
Os12g0293100	Oryza sativa	4352024
TERT	Arabidopsis thaliana	831548
TERT	Bos taurus	518884
TERT	Canis lupus familiaris	403412
tert	Danio rerio	796551
TERT	Gallus gallus	420972
TERT	Homo sapiens	7015
Tert	Mus musculus	21752
Tert	Rattus norvegicus	301965

[HomoloGene icon]

HomoloGene homology group 31141

AF_000166

E3 ubiquitin-protein ligase Topors | LUN | p53-BINDING PROTEIN 3 | P53BP3 | retinitis pigmentosa 31 (autosomal dominant) | RP11-205M20.5 | RP31 | SUMO1-protein E3 ligase Topors | topoisomerase I binding, arginine/serine-rich | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | TOPOISOMERASE I-BINDING ARGININE/SERINE-RICH PROTEIN | topoisomerase I-binding RING finger protein | TOPORS | TP53BPL | tumor suppressor p53-binding protein 3
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
si:ch211-145b13.4	Danio rerio	324197
TOPORS	Bos taurus	523321
TOPORS	Canis lupus familiaris	481577
TOPORS	Gallus gallus	427342
TOPORS	Homo sapiens	10210
TOPORS	Macaca mulatta	703930
Topors	Mus musculus	106021
TOPORS	Pan troglodytes	744660
Topors	Rattus norvegicus	362501

[HomoloGene icon]

HomoloGene homology group 4237

AF_000006

E3 ubiquitin-protein ligase Topors | LUN | p53-binding protein 3 | p53BP3 | p53BP3/LUN | RP23-9F23.3 | SUMO1-protein E3 ligase Topors | topoisomerase 1-binding RING finger | topoisomerase I binding, arginine/serine-rich | topoisomerase I-binding arginine/serine-rich protein | topoisomerase I-binding RING finger protein | Topors | TP53BPL | tumor suppressor p53-binding protein 3
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
si:ch211-145b13.4	Danio rerio	324197
TOPORS	Bos taurus	523321
TOPORS	Canis lupus familiaris	481577
TOPORS	Gallus gallus	427342
TOPORS	Homo sapiens	10210
TOPORS	Macaca mulatta	703930
Topors	Mus musculus	106021
TOPORS	Pan troglodytes	744660
Topors	Rattus norvegicus	362501

[HomoloGene icon]

HomoloGene homology group 4237

AF_000007

53BP1 | p202 | p53-binding protein 1 | p53BP1 | TP53BP1 | tumor protein 53-binding protein, 1 | tumor protein p53 binding protein 1 | TUMOR PROTEIN p53-BINDING PROTEIN 1 | tumor protein p53-binding protein, 1 | tumor suppressor p53-binding protein 1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
TP53BP1	Bos taurus	509111
TP53BP1	Canis lupus familiaris	478274
TP53BP1	Gallus gallus	415589
TP53BP1	Homo sapiens	7158
TP53BP1	Macaca mulatta	710237
Tp53bp1	Mus musculus	27223
TP53BP1	Pan troglodytes	467668
Tp53bp1	Rattus norvegicus	296099
zgc:158452	Danio rerio	557086

[HomoloGene icon]

HomoloGene homology group 4137

AF_000066

53BP1 | m53BP1 | murine p53-binding protein | p53-binding protein 1 | p53BP1 | RP23-437L13.2 | Tp53bp1 | transformation related protein 53 binding protein 1 | transformation related protein 53 binding-protein 1 | Trp53bp1 | tumor suppressor p53-binding protein 1
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
TP53BP1	Bos taurus	509111
TP53BP1	Canis lupus familiaris	478274
TP53BP1	Gallus gallus	415589
TP53BP1	Homo sapiens	7158
TP53BP1	Macaca mulatta	710237
Tp53bp1	Mus musculus	27223
TP53BP1	Pan troglodytes	467668
Tp53bp1	Rattus norvegicus	296099
zgc:158452	Danio rerio	557086

[HomoloGene icon]

HomoloGene homology group 4137

AF_000067

deltaNp63 | Ket | KET protein | P51/P63 | p51/p63 | P63 | p63 | P73l | p73L | TAp63 | Tp63 | Tp73l | transformation related protein 63 | transformation-related protein 63 | Trp53rp1 | Trp63 | tumor protein 63
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
TP63	Bos taurus	615335
TP63	Canis lupus familiaris	488125
tp63	Danio rerio	260407
TP63	Gallus gallus	374269
TP63	Homo sapiens	8626
TP63	Macaca mulatta	703997
Tp63	Mus musculus	22061
TP63	Pan troglodytes	460930
Tp63	Rattus norvegicus	246334

[HomoloGene icon]

HomoloGene homology group 31189

AF_000869

Saccharomyces cerevisiae

LMA1 | TRX1 | Trx1p | TRX2 | YLR043C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
KLLA0E16347g	Kluyveromyces lactis	2893642
LOC474798	Canis lupus familiaris	474798
LOC716456	Macaca mulatta	716456
MGG_04236	Magnaporthe oryzae	2677571
NCU06556	Neurospora crassa	3878421
Os03g0800700	Oryza sativa	4334453
Os07g0190800	Oryza sativa	4342618
Trx-2	Drosophila melanogaster	34281
TRX1	Anopheles gambiae	1278949
TRX1	Saccharomyces cerevisiae	850732
trx1	Schizosaccharomyces pombe	2542084
TRX2	Arabidopsis thaliana	833992
TRX2	Saccharomyces cerevisiae	853123
TXN	Bos taurus	280950
txn	Danio rerio	436734
TXN	Gallus gallus	396437
TXN	Homo sapiens	7295
TXN	Macaca mulatta	693792
TXN	Macaca mulatta	712587
TXN	Pan troglodytes	740248
Txn1	Mus musculus	22166
Txn1	Rattus norvegicus	116484
zgc:56493	Danio rerio	336637

[HomoloGene icon]

HomoloGene homology group 128202

AF_001042

Saccharomyces cerevisiae

END12 | L9672.10 | PEP15 | phosphatidylinositol 3-kinase VPS34 | STT8 | VPL7 | VPS34 | Vps34p | VPS7 | VPT29 | YLR240W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP010273	Anopheles gambiae	1279696
AGOS_AGL113C	Eremothecium gossypii	4622853
AT1G60490.1	Arabidopsis thaliana	842344
KLLA0D18645g	Kluyveromyces lactis	2893198
LOC100857877	Gallus gallus	100857877
MGG_03069	Magnaporthe oryzae	2682622
NCU00656	Neurospora crassa	3881921
Os05g0180600	Oryza sativa	4337982
Pi3K59F	Drosophila melanogaster	37733
pik3	Schizosaccharomyces pombe	2543444
PIK3C3	Bos taurus	534815
PIK3C3	Canis lupus familiaris	490477
pik3c3	Danio rerio	548346
PIK3C3	Homo sapiens	5289
PIK3C3	Macaca mulatta	693918
Pik3c3	Mus musculus	225326
PIK3C3	Pan troglodytes	455385
Pik3c3	Rattus norvegicus	65052
vps-34	Caenorhabditis elegans	172280
VPS34	Saccharomyces cerevisiae	850941

[HomoloGene icon]

HomoloGene homology group 1986

AF_000112

Schizosaccharomyces pombe

MAP kinase kinase Wis1 | smf2 | SPBC409.07c | spc2 | sty2 | wis1
Source:

Ageing Phenotype Observation—Data Type 1	GenDR
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP003365	Anopheles gambiae	1275042
AGOS_AFL217C	Eremothecium gossypii	4621557
KLLA0E15313g	Kluyveromyces lactis	2893728
MAP2K4	Bos taurus	526469
MAP2K4	Gallus gallus	417312
MAP2K4	Homo sapiens	6416
MAP2K4	Macaca mulatta	718155
Map2k4	Mus musculus	26398
MAP2K4	Pan troglodytes	455065
Map2k4	Rattus norvegicus	287398
map2k4a	Danio rerio	403052
MGG_10268	Magnaporthe oryzae	2681821
mkk-4	Caenorhabditis elegans	185682
Mkk4	Drosophila melanogaster	41020
NCU00587	Neurospora crassa	3881869
PBS2	Saccharomyces cerevisiae	853313
VZC374L.1	Caenorhabditis elegans	189074
wis1	Schizosaccharomyces pombe	2541055

[HomoloGene icon]

HomoloGene homology group 48159

AF_001135

5'-deoxyribose-5-phosphate lyase Ku70 | 5'-dRP lyase Ku70 | 70 kDa subunit of Ku antigen | ATP-dependent DNA helicase 2 subunit 1 | ATP-dependent DNA helicase II 70 kDa subunit | ATP-dependent DNA helicase II, 70 kDa subunit | CTA-216E10.7 | CTC box binding factor 75 kDa subunit | CTC box-binding factor 75 kDa subunit | CTC75 | CTCBF | D22S671 | D22S731 | DNA repair protein XRCC6 | G22P1 | Ku ANTIGEN, 70-KD SUBUNIT | Ku autoantigen p70 subunit | Ku autoantigen, 70kDa | KU70 | Ku70 | LUPUS AUTOANTIGEN p70 | lupus Ku autoantigen protein p70 | ML8 | thyroid autoantigen 70kD (Ku antigen) | thyroid autoantigen 70kDa (Ku antigen) | THYROID AUTOANTIGEN, 70-KD | THYROID-LUPUS AUTOANTIGEN | thyroid-lupus autoantigen p70 | TLAA | X-ray repair complementing defective repair in Chinese hamster cells 6 | X-ray repair cross-complementing protein 6 | X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 6 | XRCC6
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP002690	Anopheles gambiae	1273271
cku-70	Caenorhabditis elegans	176546
Irbp	Drosophila melanogaster	117419
KLLA0C06226g	Kluyveromyces lactis	2892291
KU70	Arabidopsis thaliana	838268
LOC100536337	Danio rerio	100536337
MGG_01512	Magnaporthe oryzae	2679155
NCU08290	Neurospora crassa	3878669
Os07g0184900	Oryza sativa	4342584
pku70	Schizosaccharomyces pombe	2539090
XRCC6	Bos taurus	510132
XRCC6	Canis lupus familiaris	474485
xrcc6	Danio rerio	334488
XRCC6	Gallus gallus	395767
XRCC6	Homo sapiens	2547
XRCC6	Macaca mulatta	707975
Xrcc6	Mus musculus	14375
XRCC6	Pan troglodytes	465902
Xrcc6	Rattus norvegicus	25019
YKU70	Saccharomyces cerevisiae	855328

[HomoloGene icon]

HomoloGene homology group 37483

AF_000036

5'-deoxyribose-5-phosphate lyase Ku70 | 5'-dRP/AP lyase Ku70 | 70kDa | ATP-dependent DNA helicase 2 subunit 1 | ATP-dependent DNA helicase II 70 kDa subunit | CTC box-binding factor 75 kDa subunit | CTC75 | CTCBF | DNA repair protein XRCC6 | G22p1 | ku autoantigen protein p70 homolog | Ku p70 | Ku70 | thyroid autoantigen 70 kDa | X-ray repair complementing defective repair in Chinese hamster cells 6 | X-ray repair cross-complementing protein 6 | Xrcc6
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP002690	Anopheles gambiae	1273271
cku-70	Caenorhabditis elegans	176546
Irbp	Drosophila melanogaster	117419
KLLA0C06226g	Kluyveromyces lactis	2892291
KU70	Arabidopsis thaliana	838268
LOC100536337	Danio rerio	100536337
MGG_01512	Magnaporthe oryzae	2679155
NCU08290	Neurospora crassa	3878669
Os07g0184900	Oryza sativa	4342584
pku70	Schizosaccharomyces pombe	2539090
XRCC6	Bos taurus	510132
XRCC6	Canis lupus familiaris	474485
xrcc6	Danio rerio	334488
XRCC6	Gallus gallus	395767
XRCC6	Homo sapiens	2547
XRCC6	Macaca mulatta	707975
Xrcc6	Mus musculus	14375
XRCC6	Pan troglodytes	465902
Xrcc6	Rattus norvegicus	25019
YKU70	Saccharomyces cerevisiae	855328

[HomoloGene icon]

HomoloGene homology group 37483

AF_000038

Saccharomyces cerevisiae

alkaline dihydroceramidase | LPG21W | YDC1 | Ydc1p | YPL087W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
ACER3	Bos taurus	615110
ACER3	Canis lupus familiaris	607939
ACER3	Gallus gallus	419087
ACER3	Homo sapiens	55331
ACER3	Macaca mulatta	697832
Acer3	Mus musculus	66190
ACER3	Pan troglodytes	748831
Acer3	Rattus norvegicus	499210
AT4G22330.1	Arabidopsis thaliana	828328
KLLA0E23981g	Kluyveromyces lactis	2894355
LOC555411	Danio rerio	555411
MGG_05619	Magnaporthe oryzae	2675865
NCU02969	Neurospora crassa	3881519
Os03g0698900	Oryza sativa	4333811
YDC1	Saccharomyces cerevisiae	856018
YPC1	Saccharomyces cerevisiae	852481

[HomoloGene icon]

HomoloGene homology group 5410

AF_001073

Saccharomyces cerevisiae

HDF1 | KU70 | NES24 | YKU70 | Yku70p | YM8021.10 | YMR284W
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP002690	Anopheles gambiae	1273271
cku-70	Caenorhabditis elegans	176546
Irbp	Drosophila melanogaster	117419
KLLA0C06226g	Kluyveromyces lactis	2892291
KU70	Arabidopsis thaliana	838268
LOC100536337	Danio rerio	100536337
MGG_01512	Magnaporthe oryzae	2679155
NCU08290	Neurospora crassa	3878669
Os07g0184900	Oryza sativa	4342584
pku70	Schizosaccharomyces pombe	2539090
XRCC6	Bos taurus	510132
XRCC6	Canis lupus familiaris	474485
xrcc6	Danio rerio	334488
XRCC6	Gallus gallus	395767
XRCC6	Homo sapiens	2547
XRCC6	Macaca mulatta	707975
Xrcc6	Mus musculus	14375
XRCC6	Pan troglodytes	465902
Xrcc6	Rattus norvegicus	25019
YKU70	Saccharomyces cerevisiae	855328

[HomoloGene icon]

HomoloGene homology group 37483

AF_000582

Saccharomyces cerevisiae

HDF2 | YKU80 | Yku80p | YM9718.05C | YMR106C
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2	Lifespan Observations Database

Gene Symbol	Species	NCBI Gene ID
AgaP_AGAP009910	Anopheles gambiae	1279324
AGOS_ABL030W	Eremothecium gossypii	4618996
KU80	Arabidopsis thaliana	841223
LOC100331090	Danio rerio	100331090
MGG_10157	Magnaporthe oryzae	2681784
NCU00077	Neurospora crassa	3872525
pku80	Schizosaccharomyces pombe	2541045
XRCC5	Bos taurus	531945
XRCC5	Canis lupus familiaris	478902
xrcc5	Danio rerio	449848
XRCC5	Gallus gallus	424222
XRCC5	Homo sapiens	7520
XRCC5	Macaca mulatta	574279
Xrcc5	Mus musculus	22596
XRCC5	Pan troglodytes	449614
Xrcc5	Rattus norvegicus	363247
YKU80	Saccharomyces cerevisiae	855132

[HomoloGene icon]

HomoloGene homology group 40681

AF_000583

Saccharomyces cerevisiae

LSB4 | YHR016C | YSC84 | Ysc84p
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
AGOS_AEL017W	Eremothecium gossypii	4621042
KLLA0A08360g	Kluyveromyces lactis	2896733
LOC606804	Canis lupus familiaris	606804
LOC721394	Macaca mulatta	721394
LSB3	Saccharomyces cerevisiae	850580
MGG_02506	Magnaporthe oryzae	2681603
NCU03888	Neurospora crassa	3873753
SH3YL1	Bos taurus	534337
sh3yl1	Danio rerio	566522
SH3YL1	Gallus gallus	421908
SH3YL1	Homo sapiens	26751
Sh3yl1	Mus musculus	24057
Sh3yl1	Rattus norvegicus	362724
SPAPJ696.02	Schizosaccharomyces pombe	2543305
YSC84	Saccharomyces cerevisiae	856409

[HomoloGene icon]

HomoloGene homology group 31662

AF_001080

14-3-3 delta | 14-3-3 protein zeta/delta | 14-3-3 protein/cytosolic phospholipase A2 | 14-3-3 zeta | 14-3-3-ZETA | 14-3-3-zeta | BRAIN PROTEIN 14-3-3, ZETA ISOFORM | KCIP-1 | phospholipase A2 | protein kinase C inhibitor protein 1 | protein kinase C inhibitor protein-1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide | TYROSINE 3-MONOOXYGENASE/TRYPTOPHAN 5-MONOOXYGENASE ACTIVATION PROTEIN, ZETA ISOFORM | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide | YWHAD | YWHAZ
Source:

Ageing Phenotype Observation—Data Type 1	GenAge
Homology Analysis Data [putative]	AgeFactDB Homology Analysis

Gene Symbol	Species	NCBI Gene ID
14-3-3zeta	Drosophila melanogaster	36059
AgaP_AGAP007643	Anopheles gambiae	1269582
ftt-2	Caenorhabditis elegans	181348
LOC100855903	Canis lupus familiaris	100855903
par-5	Caenorhabditis elegans	178113
ywhaqa	Danio rerio	399487
ywhaqb	Danio rerio	335195
YWHAZ	Gallus gallus	425619
YWHAZ	Homo sapiens	7534
YWHAZ	Macaca mulatta	709723
Ywhaz	Mus musculus	22631
YWHAZ	Pan troglodytes	472830
Ywhaz	Rattus norvegicus	25578

[HomoloGene icon]

HomoloGene homology group 56528

AF_000049