AgeFactDB - Release Info

Ageing factors from different sources are merged, if possible. Genes are merged by their NCBI gene ID, if assigned, and otherwise by the combination of gene symbol and species name. For genes with NCBI gene IDs gene symbol and species name are also available, of course. They are, however, not merged with genes for which the NCBI gene ID is not assigned, because it cannot be excluded that the same gene symbol/species combination is used for different genes. Compounds and other factors are merged by their name. Currently, the normalization for compounds and other factors is done manually, so the current release may be partially redundant for compounds and ageing factors.

The lifespan effect values from the Lifespan Observations Database are harmonized according to the lifespan change values reported (positive change = increased, negative change = decreased).

Lifespan observations, independent from the input source (currently: Lifespan Observations Database and GenAge), are significant, if the difference between observed value and base value is at least 5%. If this difference can not be determined, the significance information from the source is taken, if provided.

A homology analysis is applied for genes with experimental evidence for ageing relevance. If only lifespan data are available, the lifespan change must be greater than 5% for at least one observation to take the gene into account. For homology groups with only one experimentally known ageing-relevant gene, computational evidence for ageing relevance is assigned to all other genes but not to the experimentally known one. For homology groups with more than one experimentally known ageing relevant gene, formally computational ageing relevance is assigned to all genes including the ones with experimentally known ageing relevance.

AgeFactDB offers information on effects of ageing factors on lifespan and/or ageing phenotype. Ageing factors include genes, chemical compounds and other factors such as dietary restriction or overfeeding, heat shock, low temperature and so on. The information is taken from other source databases such as the GenAge Database and the Lifespan Observations Database, for example. In addition, new entries will be added by either manual or automatic text mining or by still other methods.

AgeFactDB makes an attempt to unify ageing factor names. Thus far, unification is only done for gene symbols and the (unified) AgeFactDB name is taken from a name source database. Currently, the AgeFactDB name is identical to the shortest preferred name suggested by the Gene/Protein Synonym Database - GPSDB. In GPSDB information from other databases such as UniProt/SwissProt or Wormbase, for example, is collected. Detailed information can be found by clicking on the GPSDB link. The table shown below lists all ageing factor names for which the AgeFactDB names differ from the original names used in the source databases. In addition to the unified name AgeFactDB provides information on many synonym names. Therefore, when searching for a gene in AgeFactDB it is not necessary to know the unified gene name in advance. The search will succeed for any of the synonym names including the name used in the source databases.

Ageing Factor Name Changes

#	Type	Original Name	Original Source	Species	AgeFactDB Name	Source of AgeFactDB Name
1	gene symbol	2-Cys Prx B	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G06290.1	GPSDB
2	gene symbol	ADA1	Lifespan Observations Database	Saccharomyces cerevisiae	HFI1	GPSDB
3	gene symbol	AKINBETA1	AgeFactDB Homology Analysis	Arabidopsis thaliana	KINB1	GPSDB
4	gene symbol	APG7	AgeFactDB Homology Analysis	Arabidopsis thaliana	ATG7	GPSDB
5	gene symbol	ARA7	AgeFactDB Homology Analysis	Arabidopsis thaliana	RABF2B	GPSDB
6	gene symbol	Arc-p34	AgeFactDB Homology Analysis	Drosophila melanogaster	Arpc2	GPSDB
7	gene symbol	ARLA1C	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G49870.1	GPSDB
8	gene symbol	ARLA1D	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G67560.1	GPSDB
9	gene symbol	AT1G12470	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G12470.1	GPSDB
10	gene symbol	AT1G16700	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G16700.1	GPSDB
11	gene symbol	AT1G18540	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL6A	GPSDB
12	gene symbol	AT1G20260	AgeFactDB Homology Analysis	Arabidopsis thaliana	VHA-B3	GPSDB
13	gene symbol	AT1G36240	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL30A	GPSDB
14	gene symbol	AT1G36310	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G36310.1	GPSDB
15	gene symbol	AT1G43670	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G43670.1	GPSDB
16	gene symbol	AT1G43860	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G43860.1	GPSDB
17	gene symbol	AT1G48830	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS7A	GPSDB
18	gene symbol	AT1G54220	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G54220.1	GPSDB
19	gene symbol	AT1G57600	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G57600.1	GPSDB
20	gene symbol	AT1G67430	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL17B	GPSDB
21	gene symbol	AT1G72730	AgeFactDB Homology Analysis	Arabidopsis thaliana	TIF4A-3	GPSDB
22	gene symbol	AT1G74050	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL6C	GPSDB
23	gene symbol	AT1G74060	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL6B	GPSDB
24	gene symbol	AT1G74270	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL35AC	GPSDB
25	gene symbol	AT1G76030	AgeFactDB Homology Analysis	Arabidopsis thaliana	VHA-B1	GPSDB
26	gene symbol	AT1G77940	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL30B	GPSDB
27	gene symbol	AT1G79010	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G79010.1	GPSDB
28	gene symbol	AT1G79890	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G79890.1	GPSDB
29	gene symbol	AT1G80670	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G80670.1	GPSDB
30	gene symbol	AT2G03870	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G03870.1	GPSDB
31	gene symbol	AT2G16940	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G16940.1	GPSDB
32	gene symbol	AT2G18030	AgeFactDB Homology Analysis	Arabidopsis thaliana	MSRA5	GPSDB
33	gene symbol	AT2G23780	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G23780.1	GPSDB
34	gene symbol	AT2G31610	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS3A	GPSDB
35	gene symbol	AT2G32000	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G32000.1	GPSDB
36	gene symbol	AT2G33410	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G33410.1	GPSDB
37	gene symbol	AT2G39390	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL35B	GPSDB
38	gene symbol	AT2G40510	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS26B	GPSDB
39	gene symbol	AT2G40590	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS26A	GPSDB
40	gene symbol	AT2G40650	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G40650.1	GPSDB
41	gene symbol	AT3G02530	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G02530.1	GPSDB
42	gene symbol	AT3G04920	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS24A	GPSDB
43	gene symbol	AT3G05060	AgeFactDB Homology Analysis	Arabidopsis thaliana	NOP5-2	GPSDB
44	gene symbol	AT3G06670	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G06670.1	GPSDB
45	gene symbol	AT3G08950	AgeFactDB Homology Analysis	Arabidopsis thaliana	HCC1	GPSDB
46	gene symbol	AT3G09100	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G09100.1	GPSDB
47	gene symbol	AT3G09440	AgeFactDB Homology Analysis	Arabidopsis thaliana	HSP70-3	GPSDB
48	gene symbol	AT3G09630	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL4A	GPSDB
49	gene symbol	AT3G10540	AgeFactDB Homology Analysis	Arabidopsis thaliana	PDPK2	GPSDB
50	gene symbol	AT3G10610	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS17C	GPSDB
51	gene symbol	AT3G10950	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL37AB	GPSDB
52	gene symbol	AT3G11630	AgeFactDB Homology Analysis	Arabidopsis thaliana	BAS1	GPSDB
53	gene symbol	AT3G12915	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G12915.1	GPSDB
54	gene symbol	AT3G13700	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G13700.1	GPSDB
55	gene symbol	AT3G13930	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G13930.1	GPSDB
56	gene symbol	AT3G16780	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL19B	GPSDB
57	gene symbol	AT3G18190	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G18190.1	GPSDB
58	gene symbol	AT3G18600	AgeFactDB Homology Analysis	Arabidopsis thaliana	RH51	GPSDB
59	gene symbol	AT3G18740	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL30C	GPSDB
60	gene symbol	AT3G21060	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G21060.1	GPSDB
61	gene symbol	AT3G27240	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G27240.1	GPSDB
62	gene symbol	AT3G28900	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL34C	GPSDB
63	gene symbol	AT3G42050	AgeFactDB Homology Analysis	Arabidopsis thaliana	VHA-H	GPSDB
64	gene symbol	AT3G45770	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G45770.1	GPSDB
65	gene symbol	AT3G46210	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G46210.1	GPSDB
66	gene symbol	AT3G49000	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G49000.1	GPSDB
67	gene symbol	AT3G53230	AgeFactDB Homology Analysis	Arabidopsis thaliana	CDC48D	GPSDB
68	gene symbol	AT3G53870	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS3B	GPSDB
69	gene symbol	AT3G55410	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G55410.1	GPSDB
70	gene symbol	AT3G56340	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS26C	GPSDB
71	gene symbol	AT4G02230	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL19C	GPSDB
72	gene symbol	AT4G02930	AgeFactDB Homology Analysis	Arabidopsis thaliana	TUFA	GPSDB
73	gene symbol	AT4G03120	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G03120.1	GPSDB
74	gene symbol	AT4G10450	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL9D	GPSDB
75	gene symbol	AT4G14300	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G14300.1	GPSDB
76	gene symbol	AT4G19130	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G19130.1	GPSDB
77	gene symbol	AT4G21110	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G21110.1	GPSDB
78	gene symbol	AT4G26770	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G26770.1	GPSDB
79	gene symbol	AT4G30800	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS11B	GPSDB
80	gene symbol	AT4G31420	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G31420.1	GPSDB
81	gene symbol	AT4G32175	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G32175.1	GPSDB
82	gene symbol	AT4G38930	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G38930.1	GPSDB
83	gene symbol	AT5G01290	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G01290.1	GPSDB
84	gene symbol	AT5G02490	AgeFactDB Homology Analysis	Arabidopsis thaliana	MED37D	GPSDB
85	gene symbol	AT5G02870	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL4D	GPSDB
86	gene symbol	AT5G03340	AgeFactDB Homology Analysis	Arabidopsis thaliana	CDC48E	GPSDB
87	gene symbol	AT5G04920	AgeFactDB Homology Analysis	Arabidopsis thaliana	VPS36	GPSDB
88	gene symbol	AT5G07090	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS4B	GPSDB
89	gene symbol	AT5G08560	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G08560.1	GPSDB
90	gene symbol	AT5G08680	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G08680.1	GPSDB
91	gene symbol	AT5G09490	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS15B	GPSDB
92	gene symbol	AT5G09500	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS15C	GPSDB
93	gene symbol	AT5G09510	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS15D	GPSDB
94	gene symbol	AT5G09880	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G09880.1	GPSDB
95	gene symbol	AT5G13430	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G13430.1	GPSDB
96	gene symbol	AT5G13440	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G13440.1	GPSDB
97	gene symbol	AT5G15640	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G15640.1	GPSDB
98	gene symbol	AT5G15700	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPOT2	GPSDB
99	gene symbol	AT5G16070	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G16070.1	GPSDB
100	gene symbol	AT5G18230	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G18230.1	GPSDB
101	gene symbol	AT5G22100	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G22100.1	GPSDB
102	gene symbol	AT5G22440	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL10AC	GPSDB
103	gene symbol	AT5G23900	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL13D	GPSDB
104	gene symbol	AT5G26680	AgeFactDB Homology Analysis	Arabidopsis thaliana	FEN1	GPSDB
105	gene symbol	AT5G26830	AgeFactDB Homology Analysis	Arabidopsis thaliana	THRRS	GPSDB
106	gene symbol	AT5G27770	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL22C	GPSDB
107	gene symbol	AT5G35530	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS3C	GPSDB
108	gene symbol	AT5G40530	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G40530.1	GPSDB
109	gene symbol	AT5G40810	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G40810.1	GPSDB
110	gene symbol	AT5G41190	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G41190.1	GPSDB
111	gene symbol	AT5G41520	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS10B	GPSDB
112	gene symbol	AT5G43640	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS15E	GPSDB
113	gene symbol	AT5G43920	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G43920.1	GPSDB
114	gene symbol	AT5G45190	AgeFactDB Homology Analysis	Arabidopsis thaliana	CYCT1-5	GPSDB
115	gene symbol	AT5G47700	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPP1C	GPSDB
116	gene symbol	AT5G59240	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS8B	GPSDB
117	gene symbol	AT5G65750	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G65750.1	GPSDB
118	gene symbol	AT5G65900	AgeFactDB Homology Analysis	Arabidopsis thaliana	RH27	GPSDB
119	gene symbol	ATCES1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G22330.1	GPSDB
120	gene symbol	ATCS	AgeFactDB Homology Analysis	Arabidopsis thaliana	CSY4	GPSDB
121	gene symbol	ATG6	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G61710.1	GPSDB
122	gene symbol	atg7	Lifespan Observations Database	Drosophila melanogaster	Atg7	GPSDB
123	gene symbol	atp1	AgeFactDB Homology Analysis	Arabidopsis thaliana	ATPA	GPSDB
124	gene symbol	ATP5	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G13450.1	GPSDB
125	gene symbol	ATSAC1B	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G66020.1	GPSDB
126	gene symbol	ATSTE24	AgeFactDB Homology Analysis	Arabidopsis thaliana	FACE1	GPSDB
127	gene symbol	ATVPS33	AgeFactDB Homology Analysis	Arabidopsis thaliana	VPS33	GPSDB
128	gene symbol	BIP1	AgeFactDB Homology Analysis	Arabidopsis thaliana	MED37A	GPSDB
129	gene symbol	BIP2	AgeFactDB Homology Analysis	Arabidopsis thaliana	MED37F	GPSDB
130	gene symbol	BUB3.1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G19590.1	GPSDB
131	gene symbol	BUB3.2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G49910.1	GPSDB
132	gene symbol	BUBR1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G33560.1	GPSDB
133	gene symbol	CAK4	AgeFactDB Homology Analysis	Arabidopsis thaliana	CDKD-2	GPSDB
134	gene symbol	cat	Lifespan Observations Database	Drosophila melanogaster	Ca-alpha1T	GPSDB
135	gene symbol	CBL	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G57050.1	GPSDB
136	gene symbol	CCT1	GenAge	Drosophila melanogaster	Cct1	GPSDB
137	gene symbol	cct1	Lifespan Observations Database	Drosophila melanogaster	Cct1	GPSDB
138	gene symbol	CDC48	AgeFactDB Homology Analysis	Arabidopsis thaliana	CDC48A	GPSDB
139	gene symbol	CELE_B0285.6	AgeFactDB Homology Analysis	Caenorhabditis elegans	B0285.6	GPSDB
140	gene symbol	CELE_T16H12.4	AgeFactDB Homology Analysis	Caenorhabditis elegans	T16H12.4	GPSDB
141	gene symbol	CG10664	AgeFactDB Homology Analysis	Drosophila melanogaster	CoIV	GPSDB
142	gene symbol	CG11015	AgeFactDB Homology Analysis	Drosophila melanogaster	CoVb	GPSDB
143	gene symbol	CG11943	AgeFactDB Homology Analysis	Drosophila melanogaster	Nup205	GPSDB
144	gene symbol	CG14815	AgeFactDB Homology Analysis	Drosophila melanogaster	Pex5	GPSDB
145	gene symbol	CG1753	AgeFactDB Homology Analysis	Drosophila melanogaster	Cbs	GPSDB
146	gene symbol	CG30194	AgeFactDB Homology Analysis	Drosophila melanogaster	CG44252	GPSDB
147	gene symbol	CG32528	AgeFactDB Homology Analysis	Drosophila melanogaster	parvin	GPSDB
148	gene symbol	CG42248	AgeFactDB Homology Analysis	Drosophila melanogaster	CG43867	GPSDB
149	gene symbol	CG5585	AgeFactDB Homology Analysis	Drosophila melanogaster	Rbbp5	GPSDB
150	gene symbol	CG7207	Lifespan Observations Database	Drosophila melanogaster	cert	GPSDB
151	gene symbol	CG8853	AgeFactDB Homology Analysis	Drosophila melanogaster	Che-13	GPSDB
152	gene symbol	Chip	Lifespan Observations Database	Mus musculus	Stub1	GPSDB
153	gene symbol	chmp6b	AgeFactDB Homology Analysis	Danio rerio	chmp6	GPSDB
154	gene symbol	CHR1	AgeFactDB Homology Analysis	Arabidopsis thaliana	DDM1	GPSDB
155	gene symbol	CHR8	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G18760.1	GPSDB
156	gene symbol	CI51	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G08530.1	GPSDB
157	gene symbol	cICDH	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G65930.1	GPSDB
158	gene symbol	CKL2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G72710.1	GPSDB
159	gene symbol	clk-1	Lifespan Observations Database	Mus musculus	Coq7	GPSDB
160	gene symbol	cox1	AgeFactDB Homology Analysis	Arabidopsis thaliana	COX1	GPSDB
161	gene symbol	COX1	AgeFactDB Homology Analysis	Caenorhabditis elegans	cox-1	GPSDB
162	gene symbol	COX1	AgeFactDB Homology Analysis	Danio rerio	mt-co1	GPSDB
163	gene symbol	COX1	AgeFactDB Homology Analysis	Drosophila melanogaster	CoI	GPSDB
164	gene symbol	COX1	AgeFactDB Homology Analysis	Mus musculus	Mtco1	GPSDB
165	gene symbol	COX1	AgeFactDB Homology Analysis	Rattus norvegicus	Mtco1	GPSDB
166	gene symbol	cycsb	AgeFactDB Homology Analysis	Danio rerio	cyc	GPSDB
167	gene symbol	CYP710A3	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G28850.1	GPSDB
168	gene symbol	delta-ADR	AgeFactDB Homology Analysis	Arabidopsis thaliana	DELTA-ADR	GPSDB
169	gene symbol	dFOXO	Lifespan Observations Database	Drosophila melanogaster	foxo	GPSDB
170	gene symbol	dlat-1	AgeFactDB Homology Analysis	Caenorhabditis elegans	F23B12.5	GPSDB
171	gene symbol	Dmp53	Lifespan Observations Database	Drosophila melanogaster	p53	GPSDB
172	gene symbol	DNMT2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G25480.1	GPSDB
173	gene symbol	Dnmt2	Lifespan Observations Database	Drosophila melanogaster	Mt2	GPSDB
174	gene symbol	DPOSH	Lifespan Observations Database	Drosophila melanogaster	POSH	GPSDB
175	gene symbol	DTS-3	Lifespan Observations Database	Drosophila melanogaster	mld	GPSDB
176	gene symbol	eef1a1l1	AgeFactDB Homology Analysis	Danio rerio	eef1a	GPSDB
177	gene symbol	ef1a-a	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	tef1a	GPSDB
178	gene symbol	egm	GenAge	Drosophila melanogaster	Egm	GPSDB
179	gene symbol	eIF-5A2	Lifespan Observations Database	Mus musculus	Eif5a2	GPSDB
180	gene symbol	EIF2	AgeFactDB Homology Analysis	Arabidopsis thaliana	TIF3F1	GPSDB
181	gene symbol	EIF2 GAMMA	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G04170.1	GPSDB
182	gene symbol	EIF3A	AgeFactDB Homology Analysis	Arabidopsis thaliana	TIF3A1	GPSDB
183	gene symbol	EIF3B-2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G25780.1	GPSDB
184	gene symbol	eif3s10	AgeFactDB Homology Analysis	Danio rerio	eif3a	GPSDB
185	gene symbol	EIF4A-2	AgeFactDB Homology Analysis	Arabidopsis thaliana	TIF4A-2	GPSDB
186	gene symbol	EIF4A1	AgeFactDB Homology Analysis	Arabidopsis thaliana	TIF4A-1	GPSDB
187	gene symbol	EMB1080	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS11A	GPSDB
188	gene symbol	EMB1968	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G21690.1	GPSDB
189	gene symbol	EMB2369	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G04350.1	GPSDB
190	gene symbol	emb2386	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL19A	GPSDB
191	gene symbol	emb2411	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G08840.1	GPSDB
192	gene symbol	emb2768	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G02660.1	GPSDB
193	gene symbol	EMB2780	AgeFactDB Homology Analysis	Arabidopsis thaliana	POLD1	GPSDB
194	gene symbol	EMB3010	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS6B	GPSDB
195	gene symbol	erg3	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	erg31	GPSDB
196	gene symbol	ERO1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AERO1	GPSDB
197	gene symbol	ERO2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AERO2	GPSDB
198	gene symbol	ESP4	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G01400.1	GPSDB
199	gene symbol	ETFBETA	AgeFactDB Homology Analysis	Arabidopsis thaliana	ETFB	GPSDB
200	gene symbol	Fak56D	AgeFactDB Homology Analysis	Drosophila melanogaster	Fak	GPSDB
201	gene symbol	FAS4	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G33390.1	GPSDB
202	gene symbol	flad-1	Lifespan Observations Database	Caenorhabditis elegans	R53.1	GPSDB
203	gene symbol	ftsh3	AgeFactDB Homology Analysis	Arabidopsis thaliana	FTSH3	GPSDB
204	gene symbol	FZF	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G24500.1	GPSDB
205	gene symbol	GDI1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G44100.1	GPSDB
206	gene symbol	GDI2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G59920.1	GPSDB
207	gene symbol	GH	Lifespan Observations Database	Rattus norvegicus	Ggh	GPSDB
208	gene symbol	Gpi1	AgeFactDB Homology Analysis	Mus musculus	Gpi	GPSDB
209	gene symbol	GPS1	AgeFactDB Homology Analysis	Arabidopsis thaliana	SPS3	GPSDB
210	gene symbol	GTF2H2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G05055.1	GPSDB
211	gene symbol	HDF1	Lifespan Observations Database	Saccharomyces cerevisiae	YKU70	GPSDB
212	gene symbol	HDF2	Lifespan Observations Database	Saccharomyces cerevisiae	YKU80	GPSDB
213	gene symbol	HOT5	AgeFactDB Homology Analysis	Arabidopsis thaliana	ADH2	GPSDB
214	gene symbol	HPR5	GenAge	Saccharomyces cerevisiae	SRS2	GPSDB
215	gene symbol	HSP101	AgeFactDB Homology Analysis	Arabidopsis thaliana	CLPB1	GPSDB
216	gene symbol	HSP60-2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G33210.1	GPSDB
217	gene symbol	hsp68	GenAge	Drosophila melanogaster	Hsp68	GPSDB
218	gene symbol	hsp68	Lifespan Observations Database	Drosophila melanogaster	Hsp68	GPSDB
219	gene symbol	hsp70	AgeFactDB Homology Analysis	Danio rerio	hsp70.1	GPSDB
220	gene symbol	Hsp70b	AgeFactDB Homology Analysis	Arabidopsis thaliana	HSP70-5	GPSDB
221	gene symbol	hsp90	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	swo1	GPSDB
222	gene symbol	HSP90.1	AgeFactDB Homology Analysis	Arabidopsis thaliana	HSP90-1	GPSDB
223	gene symbol	HTA12	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G02560.1	GPSDB
224	gene symbol	huntingtin	Lifespan Observations Database	Mus musculus	Htt	GPSDB
225	gene symbol	icl-1	Lifespan Observations Database	Caenorhabditis elegans	gei-7	GPSDB
226	gene symbol	ICU2	AgeFactDB Homology Analysis	Arabidopsis thaliana	POLA	GPSDB
227	gene symbol	IDH-V	AgeFactDB Homology Analysis	Arabidopsis thaliana	IDH5	GPSDB
228	gene symbol	IDH-VI	AgeFactDB Homology Analysis	Arabidopsis thaliana	IDH6	GPSDB
229	gene symbol	idha-1	AgeFactDB Homology Analysis	Caenorhabditis elegans	F43G9.1	GPSDB
230	gene symbol	idhb-1	AgeFactDB Homology Analysis	Caenorhabditis elegans	C37E2.1	GPSDB
231	gene symbol	Imp-L2	Lifespan Observations Database	Drosophila melanogaster	ImpL2	GPSDB
232	gene symbol	Inr	Lifespan Observations Database	Drosophila melanogaster	InR	GPSDB
233	gene symbol	keap1	GenAge	Drosophila melanogaster	Keap1	GPSDB
234	gene symbol	Lass1	AgeFactDB Homology Analysis	Mus musculus	Cers1	GPSDB
235	gene symbol	Lass5	AgeFactDB Homology Analysis	Mus musculus	Cers5	GPSDB
236	gene symbol	LOH2	AgeFactDB Homology Analysis	Arabidopsis thaliana	LAG2	GPSDB
237	gene symbol	LOS1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G56070.1	GPSDB
238	gene symbol	mars-1	GenAge	Caenorhabditis elegans	mrs-1	GPSDB
239	gene symbol	MAT3	AgeFactDB Homology Analysis	Arabidopsis thaliana	METK3	GPSDB
240	gene symbol	MCM2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G44900.1	GPSDB
241	gene symbol	mcp60	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	hsp60	GPSDB
242	gene symbol	mcs6	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	crk1	GPSDB
243	gene symbol	Megalin	AgeFactDB Homology Analysis	Drosophila melanogaster	mgl	GPSDB
244	gene symbol	MK	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G27450.1	GPSDB
245	gene symbol	MLH1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT4G09140.1	GPSDB
246	gene symbol	mMDH1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G53240.1	GPSDB
247	gene symbol	mMDH2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G15020.1	GPSDB
248	gene symbol	mnt	Lifespan Observations Database	Drosophila melanogaster	Mnt	GPSDB
249	gene symbol	MSD1	AgeFactDB Homology Analysis	Arabidopsis thaliana	SODA	GPSDB
250	gene symbol	MTHSC70-2	AgeFactDB Homology Analysis	Arabidopsis thaliana	HSP70-10	GPSDB
251	gene symbol	mtLPD1	AgeFactDB Homology Analysis	Arabidopsis thaliana	LPD1	GPSDB
252	gene symbol	mtLPD2	AgeFactDB Homology Analysis	Arabidopsis thaliana	LPD2	GPSDB
253	gene symbol	mus309	AgeFactDB Homology Analysis	Drosophila melanogaster	Blm	GPSDB
254	gene symbol	NACA2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G49470.1	GPSDB
255	gene symbol	nad7	AgeFactDB Homology Analysis	Arabidopsis thaliana	NAD7	GPSDB
256	gene symbol	nad9	AgeFactDB Homology Analysis	Arabidopsis thaliana	NAD9	GPSDB
257	gene symbol	nars-1	GenAge	Caenorhabditis elegans	nrs-1	GPSDB
258	gene symbol	NF1	GenAge	Drosophila melanogaster	Nf1	GPSDB
259	gene symbol	NF1	Lifespan Observations Database	Drosophila melanogaster	Nf1	GPSDB
260	gene symbol	NFU4	AgeFactDB Homology Analysis	Arabidopsis thaliana	NIFU4	GPSDB
261	gene symbol	NFU5	AgeFactDB Homology Analysis	Arabidopsis thaliana	NIFU5	GPSDB
262	gene symbol	NIP	Lifespan Observations Database	Drosophila melanogaster	mol	GPSDB
263	gene symbol	Nlaz	GenAge	Drosophila melanogaster	NLaz	GPSDB
264	gene symbol	NRPA2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G29940.1	GPSDB
265	gene symbol	ogdh-1	AgeFactDB Homology Analysis	Caenorhabditis elegans	T22B11.5	GPSDB
266	gene symbol	OLI2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G55920.1	GPSDB
267	gene symbol	Or83b	GenDR	Drosophila melanogaster	Orco	GPSDB
268	gene symbol	OVA9	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G25350.1	GPSDB
269	gene symbol	p66shc	Lifespan Observations Database	Mus musculus	Shc1	GPSDB
270	gene symbol	PAB4	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G23350.1	GPSDB
271	gene symbol	PANK1	AgeFactDB Homology Analysis	Arabidopsis thaliana	COAA	GPSDB
272	gene symbol	PAT2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AP3BA	GPSDB
273	gene symbol	PCNA1	AgeFactDB Homology Analysis	Arabidopsis thaliana	PCNA	GPSDB
274	gene symbol	PCNA2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G29570.1	GPSDB
275	gene symbol	pcyt-1	AgeFactDB Homology Analysis	Caenorhabditis elegans	F08C6.2	GPSDB
276	gene symbol	PDK1	AgeFactDB Homology Analysis	Arabidopsis thaliana	PDPK1	GPSDB
277	gene symbol	pex16	GenAge	Drosophila melanogaster	Pex16	GPSDB
278	gene symbol	PFI	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G71440.1	GPSDB
279	gene symbol	PHT3;1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G14040.1	GPSDB
280	gene symbol	PIMT1	AgeFactDB Homology Analysis	Arabidopsis thaliana	PCM	GPSDB
281	gene symbol	PIMT2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G50240.1	GPSDB
282	gene symbol	PIN1AT	AgeFactDB Homology Analysis	Arabidopsis thaliana	PIN1	GPSDB
283	gene symbol	Pit1	Lifespan Observations Database	Mus musculus	Pou1f1	GPSDB
284	gene symbol	PMSR1	AgeFactDB Homology Analysis	Arabidopsis thaliana	MSRA1	GPSDB
285	gene symbol	PMSR2	AgeFactDB Homology Analysis	Arabidopsis thaliana	MRSA2	GPSDB
286	gene symbol	PMSR3	AgeFactDB Homology Analysis	Arabidopsis thaliana	MSRA3	GPSDB
287	gene symbol	pog1	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	mip1	GPSDB
288	gene symbol	Pola	Lifespan Observations Database	Mus musculus	Pola1	GPSDB
289	gene symbol	PS1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G08700.1	GPSDB
290	gene symbol	qars-1	GenAge	Caenorhabditis elegans	ers-1	GPSDB
291	gene symbol	RAB7B	AgeFactDB Homology Analysis	Arabidopsis thaliana	RABG3F	GPSDB
292	gene symbol	rae-1	AgeFactDB Homology Analysis	Caenorhabditis elegans	npp-17	GPSDB
293	gene symbol	rala	AgeFactDB Homology Analysis	Danio rerio	ralaa	GPSDB
294	gene symbol	RECQI1	AgeFactDB Homology Analysis	Arabidopsis thaliana	RECQL1	GPSDB
295	gene symbol	RecQl3	AgeFactDB Homology Analysis	Arabidopsis thaliana	RECQL3	GPSDB
296	gene symbol	RGD1561086	AgeFactDB Homology Analysis	Rattus norvegicus	Rpl34l1	GPSDB
297	gene symbol	RGD1564788	AgeFactDB Homology Analysis	Rattus norvegicus	Wrn	GPSDB
298	gene symbol	RHA1	AgeFactDB Homology Analysis	Arabidopsis thaliana	RABF2A	GPSDB
299	gene symbol	RHD4	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT3G51460.1	GPSDB
300	gene symbol	RPA70C	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G45400.1	GPSDB
301	gene symbol	RPD3	Lifespan Observations Database	Drosophila melanogaster	Rpd3	GPSDB
302	gene symbol	rpl1001	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl10a	GPSDB
303	gene symbol	rpl1002	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl10b	GPSDB
304	gene symbol	rpl101	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl1b	GPSDB
305	gene symbol	rpl1702	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl17b	GPSDB
306	gene symbol	rpl1901	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl19a	GPSDB
307	gene symbol	rpl1902	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl19b	GPSDB
308	gene symbol	rpl2102	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl21b	GPSDB
309	gene symbol	rpl3001	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl30a	GPSDB
310	gene symbol	rpl3002	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl30b	GPSDB
311	gene symbol	rpl3402	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl34b	GPSDB
312	gene symbol	rpl35a	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl33b	GPSDB
313	gene symbol	rpl401	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl4b	GPSDB
314	gene symbol	rpl4302	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl43b	GPSDB
315	gene symbol	rpl901	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl9a	GPSDB
316	gene symbol	rpl902	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpl9b	GPSDB
317	gene symbol	rpp102	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rpa3	GPSDB
318	gene symbol	rps001	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps0a	GPSDB
319	gene symbol	RPS11-BETA	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS11C	GPSDB
320	gene symbol	RPS15	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS15A	GPSDB
321	gene symbol	rps1501	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps15a	GPSDB
322	gene symbol	rps1502	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps15b	GPSDB
323	gene symbol	rps1701	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps17a	GPSDB
324	gene symbol	rps2401	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps24a	GPSDB
325	gene symbol	rps403	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps4c	GPSDB
326	gene symbol	rps502	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps5b	GPSDB
327	gene symbol	RPS5A	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS5B	GPSDB
328	gene symbol	RPS5B	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS5A	GPSDB
329	gene symbol	RPS6	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS6A	GPSDB
330	gene symbol	rps601	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps6a	GPSDB
331	gene symbol	rps602	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rps6b	GPSDB
332	gene symbol	RS27A	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPS27B	GPSDB
333	gene symbol	SAC52	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL10A	GPSDB
334	gene symbol	SAG24	AgeFactDB Homology Analysis	Arabidopsis thaliana	RPL10C	GPSDB
335	gene symbol	sb:cb730	AgeFactDB Homology Analysis	Danio rerio	bub1bb	GPSDB
336	gene symbol	Sca	Lifespan Observations Database	Drosophila melanogaster	sca	GPSDB
337	gene symbol	SCN1	AgeFactDB Homology Analysis	Arabidopsis thaliana	GDI1	GPSDB
338	gene symbol	sdhC	GenAge	Drosophila melanogaster	SdhC	GPSDB
339	gene symbol	sdhC	Lifespan Observations Database	Drosophila melanogaster	SdhC	GPSDB
340	gene symbol	si:ch211-222e23.8	AgeFactDB Homology Analysis	Danio rerio	sacm1lb	GPSDB
341	gene symbol	si:dkey-18f23.10	AgeFactDB Homology Analysis	Danio rerio	ccnt1	GPSDB
342	gene symbol	SK13	AgeFactDB Homology Analysis	Arabidopsis thaliana	ASK5	GPSDB
343	gene symbol	Skp1a	AgeFactDB Homology Analysis	Mus musculus	Skp1	GPSDB
344	gene symbol	sod1	Lifespan Observations Database	Drosophila melanogaster	Sod	GPSDB
345	gene symbol	Sod1	Lifespan Observations Database	Drosophila melanogaster	Sod	GPSDB
346	gene symbol	SOD1	Lifespan Observations Database	Drosophila melanogaster	Sod	GPSDB
347	gene symbol	SOD2	Lifespan Observations Database	Drosophila melanogaster	Sod2	GPSDB
348	gene symbol	SPAC1006.07	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	tif1	GPSDB
349	gene symbol	SPAC1486.01	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	sod2	GPSDB
350	gene symbol	SPAC1486.09	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	nob1	GPSDB
351	gene symbol	SPAC1782.06c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	phb1	GPSDB
352	gene symbol	SPAC1851.02	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	slc1	GPSDB
353	gene symbol	SPAC20G8.10c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	atg6	GPSDB
354	gene symbol	SPAC22A12.12c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	rrp40	GPSDB
355	gene symbol	SPAC23G3.06	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	nop58	GPSDB
356	gene symbol	SPAC29E6.05c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	mxr1	GPSDB
357	gene symbol	SPAC31G5.04	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	lys12	GPSDB
358	gene symbol	SPAC3G6.11	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	chl1	GPSDB
359	gene symbol	SPAC3H1.09c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	avt3	GPSDB
360	gene symbol	SPAC4A8.07c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	lcb4	GPSDB
361	gene symbol	SPAC4F8.03	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	sdo1	GPSDB
362	gene symbol	SPAC5D6.13	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	vps74	GPSDB
363	gene symbol	SPBC16D10.08c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	hsp104	GPSDB
364	gene symbol	SPBC2G2.11	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	nmt1	GPSDB
365	gene symbol	SPBC365.20c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	pnc1	GPSDB
366	gene symbol	SPBC3B8.03	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	lys9	GPSDB
367	gene symbol	SPBC3F6.04c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	nop14	GPSDB
368	gene symbol	SPBC3H7.03c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	kgd1	GPSDB
369	gene symbol	SPBC4C3.07	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	eif3f	GPSDB
370	gene symbol	SPBC543.09	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	yta12	GPSDB
371	gene symbol	SPBC6B1.05c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	atg7	GPSDB
372	gene symbol	SPCC162.11c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	urk1	GPSDB
373	gene symbol	SPCC1919.03c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	amk2	GPSDB
374	gene symbol	SPCC306.08c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	MDH1	GPSDB
375	gene symbol	SPCC576.06c	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	msy1	GPSDB
376	gene symbol	SPCC794.07	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	lat1	GPSDB
377	gene symbol	STRS1	AgeFactDB Homology Analysis	Arabidopsis thaliana	RH5	GPSDB
378	gene symbol	Supt4h1	AgeFactDB Homology Analysis	Mus musculus	Supt4a	GPSDB
379	gene symbol	tars-1	GenAge	Caenorhabditis elegans	trs-1	GPSDB
380	gene symbol	TFP1	GenAge	Saccharomyces cerevisiae	VMA1	GPSDB
381	gene symbol	TOP1ALPHA	AgeFactDB Homology Analysis	Arabidopsis thaliana	TOP1	GPSDB
382	gene symbol	TOP1BETA	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT5G55310.1	GPSDB
383	gene symbol	TOPII	AgeFactDB Homology Analysis	Arabidopsis thaliana	TOP2	GPSDB
384	gene symbol	Trp53	AgeFactDB Homology Analysis	Mus musculus	Tp53	GPSDB
385	gene symbol	Trp53	GenAge	Mus musculus	Tp53	GPSDB
386	gene symbol	Trp53	Lifespan Observations Database	Mus musculus	Tp53	GPSDB
387	gene symbol	Trp53bp1	AgeFactDB Homology Analysis	Mus musculus	Tp53bp1	GPSDB
388	gene symbol	Trp53bp1	GenAge	Mus musculus	Tp53bp1	GPSDB
389	gene symbol	Trp63	AgeFactDB Homology Analysis	Mus musculus	Tp63	GPSDB
390	gene symbol	Trp63	GenAge	Mus musculus	Tp63	GPSDB
391	gene symbol	trs1	AgeFactDB Homology Analysis	Schizosaccharomyces pombe	ths1	GPSDB
392	gene symbol	Uch-L3	AgeFactDB Homology Analysis	Drosophila melanogaster	Uch-L5	GPSDB
393	gene symbol	UCH2	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G65650.1	GPSDB
394	gene symbol	UCP2	AgeFactDB Homology Analysis	Arabidopsis thaliana	PUMP2	GPSDB
395	gene symbol	UFD1	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT2G21270.1	GPSDB
396	gene symbol	VHA-A1	AgeFactDB Homology Analysis	Arabidopsis thaliana	VHA-a1	GPSDB
397	gene symbol	VPS22	AgeFactDB Homology Analysis	Arabidopsis thaliana	VP22-1	GPSDB
398	gene symbol	VPS24.1	AgeFactDB Homology Analysis	Arabidopsis thaliana	VPS24-1	GPSDB
399	gene symbol	VPS24.2	AgeFactDB Homology Analysis	Arabidopsis thaliana	VPS24-2	GPSDB
400	gene symbol	VPS34	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G60490.1	GPSDB
401	gene symbol	Wash2	AgeFactDB Homology Analysis	Rattus norvegicus	Wash1	GPSDB
402	gene symbol	wdr-5.1	GenAge	Caenorhabditis elegans	wdr-5	GPSDB
403	gene symbol	wdr26b	AgeFactDB Homology Analysis	Danio rerio	wdr26	GPSDB
404	gene symbol	wu:fi41d10	AgeFactDB Homology Analysis	Danio rerio	yars2	GPSDB
405	gene symbol	XPD	Lifespan Observations Database	Mus musculus	Ercc2	GPSDB
406	gene symbol	Y43H11AL.2	AgeFactDB Homology Analysis	Caenorhabditis elegans	laat-1	GPSDB
407	gene symbol	Y43H11AL.2	GenAge	Caenorhabditis elegans	laat-1	GPSDB
408	gene symbol	Y43H11AL.2	Lifespan Observations Database	Caenorhabditis elegans	laat-1	GPSDB
409	gene symbol	YDR049W	GenAge	Saccharomyces cerevisiae	VMS1	GPSDB
410	gene symbol	YGL085W	GenAge	Saccharomyces cerevisiae	LCL3	GPSDB
411	gene symbol	YHB4	GenDR	Saccharomyces cerevisiae	YHB1	GPSDB
412	gene symbol	YKL171W	GenAge	Saccharomyces cerevisiae	NNK1	GPSDB
413	gene symbol	YLR104W	GenAge	Saccharomyces cerevisiae	LCL2	GPSDB
414	gene symbol	YLR426W	GenAge	Saccharomyces cerevisiae	TDA5	GPSDB
415	gene symbol	YMR258C	GenAge	Saccharomyces cerevisiae	ROY1	GPSDB
416	gene symbol	YPL009C	GenAge	Saccharomyces cerevisiae	TAE2	GPSDB
417	gene symbol	YPL056C	GenAge	Saccharomyces cerevisiae	LCL1	GPSDB
418	gene symbol	zgc:158642	AgeFactDB Homology Analysis	Danio rerio	sacm1la	GPSDB
419	gene symbol	zgc:73144	AgeFactDB Homology Analysis	Danio rerio	rheb	GPSDB
420	gene symbol	ZIP4	AgeFactDB Homology Analysis	Arabidopsis thaliana	AT1G56590.1	GPSDB

AgeFactDB is a curated database. This table contains a listing of modifications that were applied to the data of the original sources. Not annotated in this table are general modifications to unify the data representation. This includes the spelling of compounds and other ageing factors. In AgeFactDB compounds and other factors are spelled in lowercase except the first letter. Exceptions for abbreviations (e.g. CCCP) and proper names (Coenzyme Q10) are allowed. Furthermore, to become independent from the variability of input sources, the lifespan effects and the significance values are derived from an own rule system. AgeFactDB provides the following qualitative significant lifespan effects: increased, decreased and none. An observed lifespan changed is significant, if the difference between observed value and base value is at least 5%. If this difference can not be determined, the significance information from the source is taken, if provided.

#	AgeFactDB Stable ID	Original Source	Original Value	Modified Value	Modification Description	Modification Comment
1	OB_000302	Lifespan Observations Database (ID: 131)			Skip import of an observation from the Lifespan Observations Database.
2	OB_000334	Lifespan Observations Database (ID: 160)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
3	OB_004200	Lifespan Observations Database (ID: 889)		Anopheles stephensi	Correct the species of an observation from the Lifespan Observations Database.
4	OB_004202	Lifespan Observations Database (ID: 890)		Anopheles stephensi	Correct the species of an observation from the Lifespan Observations Database.
5	OB_004203	Lifespan Observations Database (ID: 891)		Anopheles stephensi	Correct the species of an observation from the Lifespan Observations Database.
6	OB_004204	Lifespan Observations Database (ID: 892)		Anopheles stephensi	Correct the species of an observation from the Lifespan Observations Database.
7	OB_004205	Lifespan Observations Database (ID: 893)		Anopheles stephensi	Correct the species of an observation from the Lifespan Observations Database.
8	OB_004206	Lifespan Observations Database (ID: 894)		Anopheles stephensi	Correct the species of an observation from the Lifespan Observations Database.
9	OB_004345	Lifespan Observations Database (ID: 2272)	N-acetyl-1-cysteine	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
10	OB_004346	Lifespan Observations Database (ID: 2273)	N-acetyl-1-cysteine	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
11	OB_004347	Lifespan Observations Database (ID: 2274)	N-acetyl-1-cysteine	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
12	OB_004348	Lifespan Observations Database (ID: 2275)	N-acetyl-1-cysteine	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
13	OB_001232	Lifespan Observations Database (ID: 2560)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
14	OB_001543	Lifespan Observations Database (ID: 2885)	0	20	Correct the lifespan change of an observation from the Lifespan Observations Database.
15	OB_001543	Lifespan Observations Database (ID: 2885)	decreased	increased	Correct the lifespan effect of an observation from the Lifespan Observations Database.
16	OB_002388	Lifespan Observations Database (ID: 3656)	0	75	Correct the lifespan change of an observation from the Lifespan Observations Database.
17	OB_002399	Lifespan Observations Database (ID: 3666)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
18	OB_002662	Lifespan Observations Database (ID: 3953)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
19	OB_003059	Lifespan Observations Database (ID: 4401)		Saccharomyces cerevisiae	Correct the species of an observation from the Lifespan Observations Database.
20	OB_003108	Lifespan Observations Database (ID: 4488)	rho0	RAS2	Rename gene symbol from Lifespan Observations database.
21	OB_003153	Lifespan Observations Database (ID: 4547)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
22	OB_003167	Lifespan Observations Database (ID: 4563)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
23	OB_004945	Lifespan Observations Database (ID: 4578)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
24	OB_004955	Lifespan Observations Database (ID: 4641)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
25	OB_004496	Lifespan Observations Database (ID: 4648)	N-acetyl-cystein	N-acetyl-cysteine	Rename compound from Lifespan Observations database.	In the publication it is written with 'e' at the end, so it is not N-acetyl-cystein.
26	OB_004497	Lifespan Observations Database (ID: 4649)	N-acetyl-cystein	N-acetyl-cysteine	Rename compound from Lifespan Observations database.	In the publication it is written with 'e' at the end, so it is not N-acetyl-cystein.
27	OB_004498	Lifespan Observations Database (ID: 4650)	N-acetyl-cystein	N-acetyl-cysteine	Rename compound from Lifespan Observations database.	In the publication it is written with 'e' at the end, so it is not N-acetyl-cystein.
28	OB_004499	Lifespan Observations Database (ID: 4651)	N-acetyl-cystein	N-acetyl-cysteine	Rename compound from Lifespan Observations database.	In the publication it is written with 'e' at the end, so it is not N-acetyl-cystein.
29	OB_004500	Lifespan Observations Database (ID: 4652)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
30	OB_004504	Lifespan Observations Database (ID: 4656)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
31	OB_004508	Lifespan Observations Database (ID: 4660)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
32	OB_003240	Lifespan Observations Database (ID: 4667)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
33	OB_003279	Lifespan Observations Database (ID: 4701)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
34	OB_003280	Lifespan Observations Database (ID: 4702)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
35	OB_003281	Lifespan Observations Database (ID: 4703)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
36	OB_003480	Lifespan Observations Database (ID: 4906)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
37	OB_004543	Lifespan Observations Database (ID: 4981)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
38	OB_003572	Lifespan Observations Database (ID: 5007)	0	-13	Correct the lifespan change of an observation from the Lifespan Observations Database.
39	OB_003591	Lifespan Observations Database (ID: 5027)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
40	OB_003603	Lifespan Observations Database (ID: 5038)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
41	OB_003607	Lifespan Observations Database (ID: 5041)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
42	OB_004976	Lifespan Observations Database (ID: 5050)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
43	OB_004977	Lifespan Observations Database (ID: 5051)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
44	OB_003615	Lifespan Observations Database (ID: 5055)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
45	OB_003617	Lifespan Observations Database (ID: 5057)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
46	OB_004978	Lifespan Observations Database (ID: 5061)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
47	OB_004565	Lifespan Observations Database (ID: 5092)	increased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
48	OB_004567	Lifespan Observations Database (ID: 5100)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
49	OB_004568	Lifespan Observations Database (ID: 5101)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
50	OB_004569	Lifespan Observations Database (ID: 5102)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
51	OB_004570	Lifespan Observations Database (ID: 5103)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
52	OB_004571	Lifespan Observations Database (ID: 5104)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
53	OB_004572	Lifespan Observations Database (ID: 5105)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
54	OB_004573	Lifespan Observations Database (ID: 5106)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
55	OB_004574	Lifespan Observations Database (ID: 5107)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
56	OB_004575	Lifespan Observations Database (ID: 5108)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
57	OB_004576	Lifespan Observations Database (ID: 5109)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
58	OB_004577	Lifespan Observations Database (ID: 5110)	NAC	N-acetyl-cysteine	Rename compound from Lifespan Observations database.
59	OB_003665	Lifespan Observations Database (ID: 5185)	0	25	Correct the lifespan change of an observation from the Lifespan Observations Database.
60	OB_003667	Lifespan Observations Database (ID: 5187)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
61	OB_003668	Lifespan Observations Database (ID: 5188)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
62	OB_003777	Lifespan Observations Database (ID: 5358)	decreased	none	Correct the lifespan effect of an observation from the Lifespan Observations Database.
63	OB_005006	Lifespan Observations Database (ID: 5372)	N2	Caenorhabditis elegans	Correct the species of an observation from the Lifespan Observations Database.
64	OB_005006	Lifespan Observations Database (ID: 5372)		N2	Correct the strain of an observation from the Lifespan Observations Database.
65	OB_004942	Lifespan Observations Database (ID: 4575)	paraquat	Oxidative stress	Rename other factor from Lifespan Observations database.
66	OB_004943	Lifespan Observations Database (ID: 4576)	paraquat	Oxidative stress	Rename other factor from Lifespan Observations database.
67	OB_004975	Lifespan Observations Database (ID: 5049)	Paraquat	Oxidative stress	Rename other factor from Lifespan Observations database.
68	OB_000518	Lifespan Observations Database (ID: 177)	854598	802462	Correct NCBI Gene ID of a gene from the Lifespan Observations Database.	NCBI Gene ID 854598 belongs to gene COX1 from Saccharomyces cerevisiae (wrong species).